2. Neuronal Signaling Anti-infection
  3. Monoamine Oxidase Influenza Virus
  4. Eckol

Eckol是一种有效的 hMAO-A (混合性) 和 hMAO-B (非竞争性) 抑制剂，IC50 分别为 7.20 和 83.44 μM。Eckol 对玉米有刺激作用，可作为植物生物刺激素使用。Eckol 还显示抗过敏和抗病毒 (antiviral) 作用。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Eckol Chemical Structure

Eckol Chemical Structure

CAS No. : 88798-74-7

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Customer Review

Eckol 相关抗体

Top Publications Citing Use of Products

查看 Monoamine Oxidase 亚型特异性产品:

查看所有亚型
MAO-A MAO-B

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Eckol is a potent hMAO-A (Mixed) and hMAO-B (non-competitive) inhibitor with IC50s of 7.20 and 83.44 μM, respectively. Eckol shows stimulatory effects in maize and can be used as a plant biostimulant. Eckol also shows antiallergic and antiviral effects[1][2][3][4].

IC50 & Target[1][4]

hMAO-A

7.20 μM (IC50)

hMAO-B

83.44 μM (IC50)

H1N1

89.5 μM (IC50)

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
Vero CC50
> 200 μM
Compound: 3
Cytotoxicity against african green monkey Vero cells assessed as cell death by MTT assay
Cytotoxicity against african green monkey Vero cells assessed as cell death by MTT assay
[PMID: 23647823]
体外研究
(In Vitro)

Eckol (25-100 μg/mL; 2 h) 预处理以剂量依赖的方式显著降低 IgE/BSA 刺激的 BMCMC 中 β-hexosaminidase 的释放[3]。
Eckol (25-100 μg/mL; 1 h) 抑制 Th2 型细胞因子的产生，如 IL-4、IL-5、 IL-13 以及促炎细胞因子，如 IL-6[3]。
Eckol (25-100 μg/mL) 减弱 IgE/BSA 刺激的 BMCMC 细胞中细胞因子 mRNA 水平，如IL-1β、IL-4、IL-5、IL-6、IL-13、IFN-γ 和 TNF-α[3]。
Eckol (25-100 μg/mL; 1 h) 在 IgE/BSA 刺激的 BMCMC 中抑制 NF-κB 的激活[3]。
Eckol 抑制 influenza A/Bervig-Mission/1/18 (H1N1) 病毒，IC50 为 89.5 µM[4]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Eckol 相关抗体:

Western Blot Analysis[3]

Cell Line: Bone marrow-derived cultured mast cells (BMCMC)
Concentration: 25, 50 and 100 μg/mL
Incubation Time: 1 h
Result: Inhibited the degradation of IκB-α within the cytosol and the translocation of the NF-κB/p65 subunit into the nucleus that were induced by IgE/BSA.
体内研究
(In Vivo)

叶面喷施 Eckol (1 μM) 显著提高了茎长和根长、茎干鲜重、叶面积和叶数[2]。
Eckol (50 or 100 μg/mouse; intradermal; once) 降低被动皮肤过敏反应 (PCA) 诱导小鼠的过敏性炎症反应[3]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: BALB/c mice (8 weeks old), IgE/BSA-induced passive cutaneous anaphylaxis (PCA) model[3]
Dosage: 50 or 100 μg/mouse
Administration: Intradermal injection, applied on mice ear 2 h prior to anaphylaxis induction
Result: Reduced allergic inflammatory responses.
分子量

372.28

Formula

C18H12O9
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Eckol 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Eckol88798-74-7Monoamine OxidaseInfluenza VirusMAOβ-hexosaminidaseTh2-type cytokinesIL-1βIL-4IL-6IL-5IL-13TNF-αIFN-γBMCMCBone marrow-derived cultured mast cellsH1N1Inhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
Eckol
目录号：
HY-114203
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z