1. Anti-infection
  2. Bacterial
  3. Enterocin K1

Enterocin K1  (Synonyms: EntK1)

目录号: HY-P5203
产品使用指南

Enterocin K1 (EntK1) 是一种细菌素 bacteriocin。Enterocin K1 也是一种核糖体合成肽。Enterocin K1 通过细菌膜上的 Eep 蛋白特异性靶向粪肠球菌of Enterococcus faecalis。Enterocin K1 对 VRE 显示出有效的抗菌活性。Enterocin K1 可用与 VRE 感染的相关研究。

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Enterocin K1 Chemical Structure

Enterocin K1 Chemical Structure

CAS No. : 2764845-22-7

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Enterocin K1 (EntK1) is a bacteriocin. Enterocin K1 is a ribosomal synthetic peptide. Enterocin K1 specifically targets Enterococcus faecalis via the Eep protein on the bacterial membrane. Enterocin K1 displays a potent antibacterial activity against VRE. Enterocin K1 can be used for related studies of VRE infections[1].

体外研究
(In Vitro)

Enterocin K1 具有抗菌活性,对不同肠球菌的 MIC 值在 0.048~1.56 mg/mL 范围内[1]
Enterocin K1 (0.01、0.1和1 mg/mL) 在人全血中,没有观察到明显的红细胞溶血作用[1]
Enterocin K1 (1 mg/mL; 0-48 h) 在全血和血浆中培养后,它对细菌素的抑制作用在血浆中比在生理盐水中高 2 倍,在血液中比在血浆中高 2 倍[1]
Enterocin K1 (10 μl of 1 mg/mL; 24 h) 在 spot-on-lawn 实验中抑制细菌素的 MIC 值大多高于 25 mg/ml,具有交叉耐药性[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: bacteriocin
Concentration: 1 mg/mL
Incubation Time: 8, 24, 48 h
Result: Showed that after 8 h, the MIC of bacteriocin in saline was 0.19 mg/mL, and the MIC of bacteriocin in plasma was 0.78 mg/mL. The MIC of bacteriocin was 1.56 mg/mL in blood, 0.39 mg/mL in saline, 1.56 mg/mL in plasma, and 3.125 mg/m in blood after 48 hours.
分子量

4564.34

Formula

C218H321N53O51S2

CAS 号
Sequence

Met-Lys-Phe-Lys-Phe-Asn-Pro-Thr-Gly-Thr-Ile-Val-Lys-Lys-Leu-Thr-Gln-Tyr-Glu-Ile-Ala-Trp-Phe-Lys-Asn-Lys-His-Gly-Tyr-Tyr-Pro-Trp-Glu-Ile-Pro-Arg-Cys

Sequence Shortening

MKFKFNPTGTIVKKLTQYEIAWFKNKHGYYPWEIPRC

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Enterocin K1
目录号:
HY-P5203
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