1. Protein Tyrosine Kinase/RTK
  2. Ephrin Receptor
  3. EphA2 agonist 2

EphA2 agonist 2 (Lead compound) 是一种选择性的 EphA2 激动剂,具有抗肿瘤活性。EphA2 agonist 2 能透过血脑屏障

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EphA2 agonist 2 Chemical Structure

EphA2 agonist 2 Chemical Structure

CAS No. : 2169273-66-7

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生物活性

EphA2 agonist 2 (Lead compound) is a selective EphA2 agonist with antitumor activities. EphA2 agonist 2 can cross the BBB[1].

体外研究
(In Vitro)

EphA2 agonist 2 (Lead compound) shows antiproliferation activity with IC50 values of 2.1 ± 1.05 μM and 5.2 ± 2.56 μM against U251 EphA2 overexpressed and U251 wild type cells, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

772.94

Formula

C40H56N10O6

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
EphA2 agonist 2
目录号:
HY-146141
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