EPO mimetic peptide-1  (Synonyms: EMP-1)

EPO mimetic peptide-1 (EMP-1), a 20 amino acid peptide. EPO mimetic peptide-1 stimulates cell proliferation, affects cell cycle and induces the production of reticulocytes in vivo^[1].

EPO mimetic peptide-1 shows inhibition of tracer ¹²⁵I-labeled EPO binding with an IC₅₀ value of 0.2 μM^[1].
EPO mimetic peptide-1 (0-50 mM; 48 h) stimulates proliferation of both TF-1 and B6Sut cells in a dose-dependent manner^[1].
EPO mimetic peptide-1 (1 and 10 μM) promots erythroid colony formation from human peripheral blood and murine bone marrow^[1].
EPO mimetic peptide-1 (10 μM; 10 min) induces the phosphorylation of proteins^[1].
EPO mimetic peptide-1 (1 and 10 μM; 0-18 h) affects cell cycle^[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

EPO mimetic peptide-1 (1 and 2 mg; once) induces the production of reticulocytes over the background of endogenous in normal, untreated mice containing endogenous basal levels of EPO mice^[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

2095.36

C₉₄H₁₃₅N₂₅O₂₆S₂

186526-28-3

GGTYSCHFGPLTWVCKPQGG

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Wrighton NC, et al. Small peptides as potent mimetics of the protein hormone erythropoietin. Science. 1996 Jul 26;273(5274):458-64.  [Content Brief]