2. Protein Tyrosine Kinase/RTK
  3. FGFR
  4. FGFR1 inhibitor 7

FGFR1 inhibitor 7 (compound 5) 是 FGFR1 络氨酸激酶的抑制剂，IC50 为 0.33 nM。FGFR1 inhibitor 7 对人癌细胞系具有广谱的细胞毒性，抑制 MOLT3 的 IC50 为 2.1 μM。

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FGFR1 inhibitor 7 Chemical Structure

FGFR1 inhibitor 7 Chemical Structure

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FGFR1 inhibitor 7 相关抗体

Top Publications Citing Use of Products

查看 FGFR 亚型特异性产品:

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FGFR FGFR1 FGFR2 FGFR3 FGFR4 FGF21

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

FGFR1 inhibitor 7 (compound 5) is an inhibitor of FGFR1 Tyrosine Kinase with IC50 value of 0.33 nM. FGFR1 inhibitor 7 shows broad-spectrum cytotoxicity agasinst human cancer cell lines, and inhibits MOLT3 cells with IC50 of 2.1 μM[1].

IC50 & Target

FGFR1[1]
分子量

429.85

Formula

C25H16ClNO4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

FGFR1 inhibitor 7 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FGFR1 inhibitor 7FGFRFibroblast growth factor receptorHuCCA-1cholangiocarcinoma HepG2hepatocellular carcinoma A549lung carcinoma MOLT-3lymphoblastic leukemia T47Dhormone-dependent breast cancer and MDA-MB-231hormone-independent breast cancerInhibitorinhibitorinhibit

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目录号：
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