2. Protein Tyrosine Kinase/RTK
  3. FGFR VEGFR
  4. FGFR3-IN-2

FGFR3-IN-2 (compound 18b) 是一种有效和选择性的 FGFR3 抑制剂，抑制 FGFR3 和 VEGFR2 的 IC50 值分别为 4.1 nM 和 570 nM。FGFR3-IN-2 可用于膀胱癌的研究。

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FGFR3-IN-2 Chemical Structure

FGFR3-IN-2 Chemical Structure

CAS No. : 2428742-58-7

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FGFR3-IN-2 相关抗体

Top Publications Citing Use of Products

查看 FGFR 亚型特异性产品:

查看所有亚型
FGFR FGFR1 FGFR2 FGFR3 FGFR4 FGF21

查看 VEGFR 亚型特异性产品:

查看所有亚型
VEGFR1/Flt-1 VEGFR2/KDR/Flk-1 VEGFR3/Flt-4

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

FGFR3-IN-2 (compound 18b) is a potent and selective FGFR3 inhibitor, with IC50s of 4.1 nM and 570 nM for FGFR3 and VEGFR2, respectively. FGFR3-IN-2 can be used for the research of bladder cancer[1].

IC50 & Target[1]

FGFR3

4.1 nM (IC50)

VEGFR2

570 nM (IC50)

分子量

597.73

Formula

C28H39N9O4S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

FGFR3-IN-2 相关分类

  • 摩尔计算器

  • 稀释计算器

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× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FGFR3-IN-22428742-58-7FGFRVEGFRFibroblast growth factor receptorVascular endothelial growth factor receptorbladder cancerInhibitorinhibitorinhibit

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