1. Protein Tyrosine Kinase/RTK
  2. FGFR
  3. FGFR3-IN-4

FGFR3-IN-4 是一种选择性的 FGFR3 抑制剂,IC50 值小于 50 nM。FGFR3-IN-4 对 FGFR3 的选择性至少比 FGFR1 高 10 倍。

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FGFR3-IN-4 Chemical Structure

FGFR3-IN-4 Chemical Structure

CAS No. : 2833706-13-9

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查看 FGFR 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

FGFR3-IN-4 is a selective FGFR3 inhibitor, with an IC50 value of less than 50 nM. FGFR3-IN-4 is at least 10 fold more selective for FGFR3 than for FGFR1[1].

IC50 & Target[1]

FGFR3

< 50 nM (IC50)

体外研究
(In Vitro)

FGFR3 (example 297) 抑制 FGFR3 活性,IC50 值小于 50 nM[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

485.97

Formula

C26H24ClN7O

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
FGFR3-IN-4
目录号:
HY-148778
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