2. Membrane Transporter/Ion Channel Neuronal Signaling Metabolic Enzyme/Protease Apoptosis
  3. GABA Receptor Cytochrome P450 Apoptosis
  4. Fipronil (Standard)

Fipronil (Standard)  (Synonyms: 氟虫腈 (标准品))

目录号: HY-B0822R 纯度: ≥98%
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摩尔计算器

Fipronil (Standard) 是 Fipronil 的分析标准品。本产品用于研究及分析应用。 Fipronil 是一种广谱杀虫剂，对鳞翅目物种以及蓟马、蝗虫、蚂蚁、蟑螂、跳蚤和蜱虫有效。Fipronil 能选择性地抑制 GABA 受体，其对蟑螂和大鼠 GABA 受体的 IC50 值分别为 30 nM 和 1600 nM。谷氨酸门控氯离子通道 (GluCls) 存在于蟑螂中，但不存在于哺乳动物中，对 Fipronil 的阻断作用非常敏感。Fipronil 还可诱导 HepG2 细胞凋亡以及促进人肝细胞中 CYP1A1 和 CYP3A4 mRNA 的表达。

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Fipronil (Standard) Chemical Structure

Fipronil (Standard) Chemical Structure

CAS No. : 120068-37-3

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生物活性

Fipronil (Standard) is the analytical standard of Fipronil. This product is intended for research and analytical applications. Fipronil is a broad-spectrum insecticide effective against Lepidoptera species as well as thrips, locusts, ants, cockroaches, fleas and ticks. Fipronil selectively inhibits GABA receptor with IC50s of 30 nM and 1600 nM for cockroach and rat GABA receptors, respectively. Glutamate-gated chloride channels (GluCls), which are present in cockroaches but not in mammals, are sensitive to the blocking effect of Fipronil. Fipronil also induces apoptosis in HepG2 cells and promotes the expression of CYP1A1 and CYP3A4 mRNA in human hepatocytes.

分子量

437.15

Formula

C12H4Cl2F6N4OS
CAS 号
中文名称

氟虫腈 (标准品)；非泼罗尼 (标准品)；氟虫清 (标准品)
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

Fipronil (Standard) 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Fipronil (Standard)120068-37-3氟虫腈 (标准品)非泼罗尼 (标准品)氟虫清 (标准品)GABA ReceptorCytochrome P450ApoptosisGamma-aminobutyric acid Receptorγ-Aminobutyric acid ReceptorCYPsInhibitorinhibitorinhibit

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