2. PROTAC Protein Tyrosine Kinase/RTK Cell Cycle/DNA Damage
  3. Ligands for Target Protein for PROTAC FLT3 CDK
  4. FLT3/CDKs ligand-1

FLT3/CDKs ligand-1 (Compound 14) 是靶蛋白的配体，可促进细胞周期蛋白依赖性激酶 (CDK) 和 FMS 样酪氨酸激酶 3 (FLT3) 的降解，抑制 FLT3/CDK 相关的白血病细胞增殖和存活。FLT3/CDKs ligand-1 可用于合成 PROTAC FLT3/CDKs Degrader-1 (HY-161708)。

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FLT3/CDKs ligand-1 Chemical Structure

FLT3/CDKs ligand-1 Chemical Structure

CAS No. : 2452019-67-7

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FLT3/CDKs ligand-1 相关抗体

Top Publications Citing Use of Products

查看 CDK 亚型特异性产品:

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CDK1 CDK2 CDK3 CDK4 CDK5 CDK6 CDK7 CDK8 CDK9 CDK11 CDK12 CDK13 CDK14 CDK16 CDK19 CDC CLK Pho85

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

FLT3/CDKs ligand-1 (Compound 14) is a ligand for target protein, which promotes the degradation of cyclin-dependent kinase (CDK) and the FMS-like tyrosine kinase 3 (FLT3), inhibits FLT3/CDK related proliferations and survivals of leukemia cells. LT3/CDKs ligand-1 can be used for synthesis of PROTAC FLT3/CDKs degrader-1 (HY-161708)[1].

分子量

517.58

Formula

C26H31N9O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

FLT3/CDKs ligand-1 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

FLT3/CDKs ligand-12452019-67-7Ligands for Target Protein for PROTACFLT3CDKTarget Protein-binding MoietyCluster of differentiation antigen 135CD135Fms like tyrosine kinase 3Cyclin dependent kinaseHL-60MV4-11THP-1KASUMI-1MOLM-13,NB-4OCI-AML-2acute myeloid leukemiaInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-161709
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