1. Antibody-drug Conjugate/ADC Related PROTAC
  2. ADC Linker PROTAC Linkers
  3. Fmoc-NH-PEG6-CH2COOH

Fmoc-NH-PEG6-CH2COOH 

目录号: HY-130364 纯度: ≥98.0%
COA 产品使用指南

Fmoc-NH-PEG6-CH2COOH 是一种可降解的ADC linker,用于抗体活性分子偶联物 (ADC) 合成。Fmoc-NH-PEG6-CH2COOH 也是一种基于 PEG 的 PROTAC linker,可用于 PROTAC 的合成。

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Fmoc-NH-PEG6-CH2COOH Chemical Structure

Fmoc-NH-PEG6-CH2COOH Chemical Structure

CAS No. : 437655-96-4

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     可免费申领三个不同产品的试用装。

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规格 价格 是否有货 数量
25 mg ¥150
In-stock
50 mg ¥240
In-stock
100 mg ¥365
In-stock
250 mg ¥600
In-stock
1 g ¥2290
询价
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10 g   询价  

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Fmoc-NH-PEG6-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG6-CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target[1]

Cleavable Linker

 

Alkyl/ether

 

PEGs

 

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

561.62

Formula

C29H39NO10

CAS 号
性状

粘稠液体

颜色

Colorless to light yellow

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Fmoc-NH-PEG6-CH2COOH
目录号:
HY-130364
需求量: