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  3. Folate-FTIC

Folate-FTIC (EC-17) 是一种叶酸衍生物,与荧光素异硫氰酸盐 (FITC) 结合,使其具有荧光标记的特性。Folate-FTIC 用于诱导抗 FITC CAR-T 细胞 (嵌合抗原受体T细胞) 与表达叶酸受体 (FRα 或 FRβ) 的靶细胞之间形成伪免疫学突触。Folate-FTIC 可用于开发可控的 CAR-T 细胞治疗方法,用于非小细胞肺癌 (NSCLC) 的研究。

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Folate-FTIC Chemical Structure

Folate-FTIC Chemical Structure

CAS No. : 583037-91-6

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Folate-FTIC 的其他形式现货产品:

Other Forms of Folate-FTIC:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Folate-FTIC (EC-17) is a folic acid derivative that binds to fluorescein isothiocyanate (FITC) to give it fluorescent labeling properties. Folate-ftic is used to induce the formation of pseudo-immunological synapses between anti-FITC CAR T cells and target cells expressing Folate receptors (FRα or FRβ). Folate-FTIC can be used to develop controlled CAR-T cell therapies for research in non-small cell lung cancer (NSCLC)[1].

分子量

872.86

Formula

C42H36N10O10S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Folate-FTIC
目录号:
HY-13615
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