2. GPCR/G Protein
  3. Guanylate Cyclase
  4. Formycin triphosphate

Formycin triphosphate 是 ATP 的荧光类似物，与酶活性位点结合后会表现出增强的荧光。Formycin triphosphate 是一种 ATP 竞争性鸡肝丙酮酸羧化酶 (pyruvate carboxylase) 抑制剂。Formycin triphosphate 可增强心房利钠因子 (ANF) 刺激的鸟苷酸环化酶 (guanylate cyclase) 活性，EC50 约为 90 μM，并抑制 ATP 刺激的鸟苷酸环化酶活性，IC50 约为 100 μM。

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Formycin triphosphate Chemical Structure

Formycin triphosphate Chemical Structure

CAS No. : 16409-13-5

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Formycin triphosphate 相关抗体

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  • 生物活性

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生物活性

Formycin triphosphate is a fluorescent analogue of ATP which on binding to enzyme active sites exhibits enhanced fluorescence. Formycin triphosphate is an ATP-competitive chicken liver pyruvate carboxylase inhibitor. Formycin triphosphate potentiates atrial natriuretic factor (ANF)-stimulated guanylate cyclase activity with an EC50 at about 90 μM and inhibits ATP-stimulated guanylate cyclase activity with an IC50 at about 100 μM[1][2].

分子量

507.18

Formula

C10H16N5O13P3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Formycin triphosphate 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

Formycin triphosphate16409-13-5Guanylate CyclaseATP fluorescent analogpyruvate carboxylaseATP-competitiveInhibitorinhibitorinhibit

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