2. Metabolic Enzyme/Protease
  3. Proteasome Factor Xa
  4. Gabexate mesylate (Standard)

Gabexate mesylate (Standard)  (Synonyms: 甲磺酸加贝酯 (Standard))

目录号: HY-B0385R 纯度: ≥98%
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Gabexate (mesylate) (Standard) 是 Gabexate (mesylate) 的分析标准品。本产品用于研究及分析应用。Gabexate mesylate (FOY) 是一种竞争性非抗原性合成胰蛋白酶样丝氨酸蛋白酶抑制剂。Gabexate mesylate 抑制人凝血酶、尿激酶、纤溶酶和 Xa 因子，Ki 分别为 0.97、1.3、1.6 和 8.5 μM。Gabexate mesylate 与人和牛类胰蛋白酶结合，Ki 分别为 3.4 nM 和 18 μM。Gabexate mesylate 对凝血酶的凝血活性发挥抗凝作用，并通过抑制 NF-κB、促炎细胞因子和一氧化氮发挥抗炎作用。Gabexate mesylate 用于胰腺炎和弥散性血管内凝血。

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Gabexate mesylate (Standard) Chemical Structure

Gabexate mesylate (Standard) Chemical Structure

CAS No. : 56974-61-9

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生物活性

Gabexate (mesylate) (Standard) is the analytical standard of Gabexate (mesylate). This product is intended for research and analytical applications. Gabexate mesylate (FOY) is is a competitive and non-antigenic synthetic inhibitor of trypsin-like serine proteinases. Gabexate mesylate inhibits human thrombin, urokinase, plasmin, and Factor Xa with Kis of 0.97, 1.3, 1.6, and 8.5 μM, respectively. Gabexate mesylate binds to human and bovine tryptase with Kis of 3.4 nM and 18 μM, respectively. Gabexate mesylate exerts an anticoagulant effect on the clotting activity of thrombin and has anti-inflammatory effect by viainhibition of NF-κB, proinflammatory cytokines, and nitric oxide. Gabexate mesylate is used for pancreatitis and disseminated intravascular coagulation.

分子量

417.48

Formula

C17H27N3O7S
CAS 号
中文名称

甲磺酸加贝酯 (Standard)
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

Gabexate mesylate (Standard) 相关分类

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Keywords:

Gabexate mesylate (Standard)56974-61-9甲磺酸加贝酯 (Standard)ProteasomeFactor XaFxaCompetitivenon-antigenictrypsin-like serine proteinasethrombinurokinaseplasmintryptaseanticoagulantanti-inflammatoryviainhibitionNF-κBproinflammatory cytokinesnitric oxidepancreatitisdisseminated intravascular coagulationInhibitorinhibitorinhibit

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