2. Immunology/Inflammation
  3. Toll-like Receptor (TLR)
  4. Ganglioside GD1a

Ganglioside GD1a通过防止 TLR4 转移到脂筏中来调节 E. coli 脂多糖的毒性和炎症效应。Ganglioside GD1a 显著减少了LPS对细胞存活率的降低作用以及刺激活性氧物种产生的影响。

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Ganglioside GD1a Chemical Structure

Ganglioside GD1a Chemical Structure

CAS No. : 12707-58-3

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Ganglioside GD1a 相关抗体

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  • 生物活性

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  • 参考文献

生物活性

Ganglioside GD1a modulates toxic and inflammatory effects of E. coli lipopolysaccharide by preventing TLR4 translocation into lipid rafts. Ganglioside GD1a significantly reduces the effect of LPS on the decrease of cell survival and on stimulation of reactive oxygen species production[1].

CAS 号
运输条件

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储存方式

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参考文献

Ganglioside GD1a 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

Ganglioside GD1a12707-58-3Toll-like Receptor (TLR)TLR4inflammatoryLPSreactive oxygen speciesInhibitorinhibitorinhibit

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