2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Ganglioside GD1b Disodium Salt (Bovine Brain)

Ganglioside GD1b Disodium Salt (Bovine Brain)  (Synonyms: Disialoganglioside GD1b; Ganglioside C1; Ganglioside G2)

目录号: HY-W747597
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Ganglioside GD1b Disodium Salt (Bovine Brain) (Disialoganglioside GD1b; Ganglioside C1) 是一种酸性糖鞘脂，含有两个唾液酸残基，与内部半乳糖单元相连。它是质膜的组成部分，与胆固醇紧密堆积，形成脂质微区，调节细胞内和细胞间的信号传导事件。人脑中Ganglioside GD1b Disodium Salt (Bovine Brain) (Disialoganglioside GD1b; Ganglioside C1) 的浓度随着年龄的增长而增加，占 0 至 10 岁受试者脑部总唾液酸的 7.85%，占 11 至 30 岁受试者脑部总唾液酸的 20.29%。Ganglioside GD1b Disodium Salt (Bovine Brain) (Disialoganglioside GD1b; Ganglioside C1) 水平与毛细胞星形细胞瘤肿瘤等级呈正相关，并且 GD1b 已在各种其他神经胶质瘤中检测到，包括原始神经外胚层肿瘤、胶质母细胞瘤和间变性星形细胞瘤。本产品含有主要具有 C18:0 脂肪酰基链长的Ganglioside GD1b Disodium Salt (Bovine Brain) (Disialoganglioside GD1b; Ganglioside C1) 分子种类。

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Ganglioside GD1b Disodium Salt (Bovine Brain) Chemical Structure

Ganglioside GD1b Disodium Salt (Bovine Brain) Chemical Structure

CAS No. : 19553-76-5

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Ganglioside GD1b Disodium Salt (Bovine Brain) 相关抗体

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生物活性

Ganglioside GD1b is an acidic glycosphingolipid that contains two sialic acid residues linked to an inner galactose unit. It is a component of plasma membranes where it packs densely with cholesterol to form lipid microdomains that modulate both intra- and intercellular signaling events. The concentration of ganglioside GD1b in human brain increases with age, constituting 7.85% of total sialic acid in the brain of 0- to 10-year-old subjects and 20.29% in 11- to 30-year-old subjects.2 Ganglioside GD1b levels are positively correlated with pilocytic astrocytoma tumor grade, and GD1b has been detected in various other gliomas, including primitive neuroectodermal tumors, glioblastomas, and anaplastic astrocytomas.3 This product contains ganglioside GD1b molecular species with primarily C18:0 fatty acyl chain lengths.

分子量

1882.04

Formula

C₈₄H₁₄₆N₄Na₂O₃₉
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Ganglioside GD1b Disodium Salt (Bovine Brain) 相关分类

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Keywords:

Ganglioside GD1b Disodium Salt (Bovine Brain)19553-76-5Disialoganglioside GD1b Ganglioside C1 Ganglioside G2Ganglioside C1Ganglioside C 1Ganglioside C-1Ganglioside G2Ganglioside G 2Ganglioside G-2Endogenous MetaboliteInhibitorinhibitorinhibit

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