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  4. Ganglioside GM2, Asialo

Ganglioside GM2, Asialo  (Synonyms: GA2神经节苷脂; Gangliotriosylceramide)

目录号: HY-W127461
产品使用指南

摩尔计算器

神经节苷脂 GM2 asialo (asialo-GM2) 是一种糖鞘脂，含有三个单糖残基和一个链长可变的脂肪酸，但缺少神经节苷脂 M2 上存在的唾液酸残基。 Asialo-GM2 在正常人脑中的水平很低，甚至检测不到，但它会在泰-萨克斯病和桑德霍夫病患者的大脑中积累，这两种疾病是分别以溶酶体 β-己糖胺酶 A 和 B 缺乏为特征的神经退行性疾病。它还与各种细菌结合，包括从囊性纤维化患者分离出的假单胞菌。 Asialo-GM2 混合物包含神经节苷脂 GM2 asialo 分子种类，具有可变长度的脂肪酰链。

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Ganglioside GM2, Asialo Chemical Structure

Ganglioside GM2, Asialo Chemical Structure

CAS No. : 35960-33-9

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规格 价格 是否有货 数量
100 μg ￥16200
3 - 4 周

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Ganglioside GM2, Asialo 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

生物活性

Ganglioside GM2 asialo (asialo-GM2) is a glycosphingolipid containing three monosaccharide residues and one fatty acid of variable chain length, but lacks the sialic acid residue present on ganglioside M2. Asialo-GM2 is found at low or undetectable levels in normal human brains, but it accumulates in the brains of patients with Tay-Sachs disease and Sandhoff disease, which are expressed as lysosomal β- A neurodegenerative disorder characterized by hexosaminidase A and B deficiency. It also binds to various bacteria, including Pseudomonas isolated from cystic fibrosis patients. The Asialo-GM2 mixture contains ganglioside GM2 asialo molecular species with fatty acyl chains of variable length.

分子量

1093.43

Formula

C56H104N2O18
CAS 号
中文名称

GA2神经节苷脂
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

Ganglioside GM2, Asialo 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ganglioside GM2, Asialo35960-33-9GangliotriosylceramideGA2神经节苷脂Biochemical Assay Reagentsbiochemical assayreagentInhibitorinhibitorinhibit

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