MYZAP - myocardial zonula adherens protein Gene

中文名称：心肌粘着带蛋白

种属: Homo sapiens

同用名: Gup; GCOM1; MYOZAP

关于 MYZAP

功能概要

该基因编码一种在心脏组织中大量表达的蛋白质。编码的蛋白质定位于心肌细胞中的椎间盘，并作为 Rho 依赖性血清反应因子信号传导的激活剂发挥作用。可变剪接导致多个转录本变体。 Readthrough 转录也存在于该基因和邻近的下游基因 POLR2M (聚合酶 (RNA) II (DNA 定向) 多肽 M) 之间，用 GeneID 表示：145781。[RefSeq 提供，2014 年 3 月]

This gene encodes a protein that is abundantly expressed in cardiac tissue. The encoded protein localizes to intercalated discs in cardiomyocytes and functions as an activator of Rho-dependent serum-response factor signaling. Alternative splicing results in multiple transcript variants. Readthrough transcription also exists between this gene and the neighboring downstream gene POLR2M (polymerase (RNA) II (DNA directed) polypeptide M) and is represented with GeneID: 145781. [provided by RefSeq, Mar 2014]