1. Gene
  2. EMC8 - ER membrane protein complex subunit 8 Gene

EMC8 - ER membrane protein complex subunit 8 Gene

中文名称:ER 膜蛋白复合亚基 8

种属: Homo sapiens

同用名: NOC4; COX4NB; C16orf2; C16orf4; FAM158B

基因 ID: 10328 | 基因类型: protein coding

关于 EMC8

Cytogenetic location: 16q24.1 Genomic coordinates (GRCh38): 16:85,778,624-85,799,544 (from NCBI)

This gene has 6 transcripts (splice variants), 208 orthologues and 1 paralogue. Ubiquitous expression in bone marrow (RPKM 7.1), testis (RPKM 6.1) and 25 other tissues.

功能概要

有助于膜插入酶活性。通过停止转移膜锚序列和尾部锚定膜蛋白插入 ER 膜参与蛋白质插入 ER 膜。位于胞质溶胶中。 EMC 复合体的一部分。 [由基因组资源联盟提供,2022 年 4 月]

Contributes to membrane insertase activity. Involved in protein insertion into ER membrane by stop-transfer membrane-anchor sequence and tail-anchored membrane protein insertion into ER membrane. Located in cytosol. Part of EMC complex. [provided by Alliance of Genome Resources, Apr 2022]

EMC8 基因产物(2)

mRNA Protein Name
NM_001142288.2 NP_001135760.1 ER membrane protein complex subunit 8 isoform 2
NM_006067.5 NP_006058.1 ER membrane protein complex subunit 8 isoform 1

EMC8 蛋白结构

UPF0172

UPF0172: Uncharacterised protein family (UPF0172) (1 - 204)

  • 0
  • 100
  • 210 a.a.
蛋白主名 其他名称

ER membrane protein complex subunit 8

COX4 neighbor

重组 EMC8 蛋白

目录号 产品名 蛋白编号 纯度
HY-P77342 COX4NB Protein, Human (His) O43402-1 (M1-C210) ≥95%

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta EMC8 VGNC VGNC:72259
Canis familiaris EMC8 VGNC VGNC:40337
Rattus norvegicus EMC8 RGD RGD:1311219
Bos taurus EMC8 VGNC VGNC:28467
Mus musculus EMC8 MGD MGI:1343095