KERA - keratocan Gene

中文名称：角质素

种属: Homo sapiens

同用名: KTN; CNA2; SLRR2B

基因 ID: 11081 | 基因类型: protein coding

关于 KERA

Cytogenetic location: 12q21.33 Genomic coordinates (GRCh38): 12:91,050,491-91,058,024 (from NCBI)

This gene has 1 transcript (splice variant), 203 orthologues, 10 paralogues and is associated with 3 phenotypes. Low expression observed in reference dataset.

功能概要

该基因编码的蛋白质是一种参与角膜透明度的硫酸角质素蛋白多糖。该基因的缺陷是常染色体隐性角膜平面 2 (CNA2) 的原因。[RefSeq 提供，2010 年 5 月]

The protein encoded by this gene is a keratan sulfate proteoglycan that is involved in corneal transparency. Defects in this gene are a cause of autosomal recessive cornea plana 2 (CNA2).[provided by RefSeq, May 2010]

KERA 基因产物(1)

mRNA	Protein	Name
NM_007035.4	NP_008966.1	keratocan precursor

KERA 蛋白结构

LRRNT

LRR_8

0
100
200
300
352 a.a.

蛋白主名

其他名称

keratocan

keratan sulfate proteoglycan keratocan

关联疾病

疾病名称

别名

Cornea Plana 2, Autosomal Recessive

CNA2	Cornea Plana Congenita, Recessive

Congenital Cornea Plana

Cornea Plana

Flat Cornea

Keratoconus

Kc	Conical Cornea
Noninflammatory Corneal Thining	Bulging Cornea
Cornea Conical	Acquired Conus Of Cornea

Cloacogenic Carcinoma

Cloacogenic Anal Carcinoma

Macular Dystrophy, Corneal

Macular Corneal Dystrophy	MCD
Corneal Dystrophy, Macular Type	Groenouw Type Ii Corneal Dystrophy
Fehr Corneal Dystrophy	Macular Dystrophy, Corneal Type 1
Mcdc1	Macular Corneal Dystrophy Type Ii
Macular Corneal Dystrophy, Type Ii	Macular Corneal Dystrophy, Type I
Mcdc1, Formerly	Macular Dystrophy, Corneal, 1
Macular Corneal Dystrophy Type 1	Corneal Dystrophy Groenouw Type Ii
Corneal Dystrophy Macular Type	Macular Corneal Dystrophy Type I
Dystrophy, Macular, Corneal

Stromal Dystrophy

Corneal Ectasia

Corneal Dystrophy, Posterior Amorphous

Posterior Amorphous Corneal Dystrophy	PACD
Chromosome 12q21.33 Deletion Syndrome	Posterior Amorphous Stromal Dystrophy

Corneal Dystrophy

Accommodative Esotropia

Esotropia With Accommodative Compensation

Exposure Keratitis

Exposure Keratoconjunctivitis

Lagophthalmic Keratitis

Corneal Dystrophy, Congenital Stromal

Congenital Stromal Corneal Dystrophy	CSCD
Congenital Hereditary Stromal Dystrophy	Congenital Hereditary Stromal Dystrophy Of The Cornea
Congenital Stromal Dystrophy Of The Cornea	Dacs
Decorin-Associated Congenital Stromal Corneal Dystrophy	Dystrophia Corneae Parenchymatosa Congenita
Witschel Dystrophy	Dystrophy, Corneal, Stromal, Congenital

Irregular Astigmatism

Corneal Ulcer

Cornea Ulcer	Ulcerative Keratitis
Corneal Ulcer Nos

Corneal Disease

Corneal Diseases

Corneal Disorders

Corneal Edema

Corneal Oedema

Infiltrate Of Cornea

Sclerocornea

Isolated Congenital Sclerocornea

Bullous Keratopathy

Bk - [Bullous Keratopathy]

Corneal Degeneration

Degenerative Corneal Opacity

Refractive Error

Refractive Errors

Eye Accommodation Disease

Keratopathy

Steroid-Induced Glaucoma

Corticosteroid-Induced Glaucoma

Nanophthalmos

Nanophthalmia

Keratitis, Hereditary

Keratitis	Autosomal Dominant Keratitis
Hereditary Keratitis	Dominantly Inherited Keratitis
Keratitis Hereditary	KERH

Axenfeld-Rieger Syndrome

Axenfeld Syndrome	Rieger Syndrome
Rieger Anomaly	Axenfeld Anomaly
Anomaly, Rieger'S	Hagedoom Syndrome
Rgs - Rieger Syndrome	Rieger'S Anomaly
Goniodysgenesis Hypodontia	Iridogoniodysgenesis With Somatic Anomalies
Ars	Axenfeld And Rieger Anomaly
Axra	Axrs
Rieger Eye Malformation Sequence

Fuchs' Endothelial Dystrophy

Fuchs Endothelial Corneal Dystrophy	Fuchs Endothelial Dystrophy
Fuchs Dystrophy	Fced
Fuchs' Corneal Dystrophy	Fuchs' Endothelial Corneal Dystrophy
Fuchs Atrophy	Fuchs Corneal Dystrophy
Endoepithelial Corneal Dystrophy	Fecd
Late Hereditary Endothelial Dystrophy	Corneal Dystrophy, Fuchs Endothelial
Dystrophy, Corneal, Fuchs Endothelial	Corneal Dystrophy, Fuchs' Endothelial, 1

Anterior Segment Dysgenesis

Anterior Segment Developmental Anomaly	Anterior Segment Mesenchymal Dysgenesis
Corneal Opacification And Other Ocular Anomalies	Sclerocornea With Other Ocular Anomalies
Asmd	Asod
Anterior Segment Ocular Dysgenesis	Foxe3-Related Ocular Disorder
Familial Ocular Anterior Segment Mesenchymal Dysgenesis	Dysgenesis, Anterior Segment
Irido-Corneal Dysgenesis	Axenfeld-Rieger Syndrome, Type 3

Aniridia 1

Aniridia	Congenital Aniridia
AN1	An
Cataract With Late-Onset Corneal Dystrophy	Aplasia Of Iris
Absent Iris	Irideremia
Aniridia Ii, Formerly	An2, Formerly
An2	Aniridia Type Ii
Aniridia, Type 1	An-1
Absence Of Iris	Agenesis Of Iris
Congenital Absence Of Iris	Hereditary Aniridia
Sporadic Aniridia

Eye Disease

Eye Diseases	Abnormality Of The Eye
Toxoplasma Oculopathy

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-E70193	Keratinase		/	否
HY-RS07234	KERA Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Canis familiaris	KERA	VGNC	VGNC:42334
Mus musculus	KERA	MGD	MGI:1202398
Rattus norvegicus	KERA	RGD	RGD:1305816
Macaca mulatta	KERA	VGNC	VGNC:108355
Bos taurus	KERA	VGNC	VGNC:30539
Macaca fascicularis	KERA	NCBI	NCBI:101866275
Others	KERA	NCBI

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站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

KERA - keratocan Gene

关于 KERA

功能概要

KERA 基因产物(1)

KERA 蛋白结构

关联疾病

直系同源

热门区域

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KERA - keratocan Gene

关于 KERA

功能概要

KERA 基因产物(1)

KERA 蛋白结构

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z