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  3. MRGPRX4 - MAS related GPR family member X4 Gene

MRGPRX4 - MAS related GPR family member X4 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：MAS 相关 GPR 家族成员 X4

种属: Homo sapiens

同用名: GPCR; MRGX4; SNSR6

基因 ID: 117196 | 基因类型: protein coding

关于 MRGPRX4

Cytogenetic location: 11p15.1 Genomic coordinates (GRCh38): 11:18,172,837-18,174,280 (from NCBI)

This gene has 1 transcript (splice variant), 444 orthologues and 10 paralogues.

功能概要

预计可启用 G 蛋白偶联受体活性。预测参与 G 蛋白偶联受体信号通路。预计在化学感应行为和造血祖细胞分化的上游或内部起作用。预测位于质膜中。预计是膜的组成部分。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within chemosensory behavior and hematopoietic progenitor cell differentiation. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

MRGPRX4 基因产物(1)

mRNA Protein Name
NM_054032.3 NP_473373.2 mas-related G-protein coupled receptor member X4

MRGPRX4 蛋白结构

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (44 - 272)

  • 0
  • 100
  • 200
  • 300
  • 322 a.a.
蛋白主名 其他名称

mas-related G-protein coupled receptor member X4

G protein-coupled receptor MRGX4

关联疾病

疾病名称 别名
Congenital Disorder Of Glycosylation, Type Ip

CDG1P

Congenital Disorder Of Glycosylation Ip

Congenital Disorder Of Glycosylation 1p

Alg11-Cdg

Cdg-Ip

Congenital Disorder Of Glycosylation Type Ip

Cdg Syndrome Type Ip

Carbohydrate Deficient Glycoprotein Syndrome Type Ip

Congenital Disorder Of Glycosylation Type 1p

Cdgip

Cdg Ip

Glycosylation, Congenital Disorder Of, Type Ip
Intrahepatic Cholestasis Of Pregnancy

Recurrent Intrahepatic Cholestasis Of Pregnancy

Gravidic Intrahepatic Cholestasis

Pregnancy-Related Cholestasis

Icp

Pregnancy Related Cholestasis

Cholestasis, Intrahepatic Of Pregnancy

Familial Intrahepatic Cholestasis Of Pregnancy

Familial Recurrent Intrahepatic Cholestasis Of Pregnancy

Ricp

Obstetric Cholestasis
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-148244 MS47134 99.88% 否
HY-147051 MRGPRX4 modulator-2 99.64% 否
HY-145997 MRGPRX4 modulator-1 99.09% 否
HY-155480 PSB-22034 Agonist / 否
HY-RS08652 MRGPRX4 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-W354369 1-(4-Fluorobenzyl)-1H-indazole-3-carboxylic acid Antagonist / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus MRGPRX4 RGD RGD:632284
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