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  2. GPR180 - G protein-coupled receptor 180 Gene

GPR180 - G protein-coupled receptor 180 Gene

中文名称:G 蛋白偶联受体 180

种属: Homo sapiens

同用名: ITR

基因 ID: 160897 | 基因类型: protein coding

关于 GPR180

Cytogenetic location: 13q32.1 Genomic coordinates (GRCh38): 13:94,601,857-94,634,661 (from NCBI)

This gene has 1 transcript (splice variant), 205 orthologues and 1 paralogue. Ubiquitous expression in fat (RPKM 4.6), thyroid (RPKM 2.7) and 25 other tissues.

功能概要

该基因编码的蛋白质是 G 蛋白偶联受体超家族的成员。这种蛋白质主要在血管平滑肌细胞中产生,可能在血管重塑的调节中发挥重要作用。[RefSeq 提供,2008 年 7 月]

This gene encodes a protein that is a member of the G protein-coupled receptor superfamily. This protein is produced predominantly in vascular smooth muscle cells and may play an important role in the regulation of vascular remodeling. [provided by RefSeq, Jul 2008]

GPR180 基因产物(1)

mRNA Protein Name
NM_180989.6 NP_851320.1 integral membrane protein GPR180 precursor

GPR180 蛋白结构

GpcrRhopsn4

GpcrRhopsn4: Rhodopsin-like GPCR transmembrane domain (143 - 405)

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  • 440 a.a.
蛋白主名 其他名称

integral membrane protein GPR180

intimal thickness-related receptor

关联疾病

疾病名称 别名
Bladder Neck Obstruction

Obstruction Of Bladder Neck Or Vesicourethral Orifice

Urinary Bladder Neck Obstruction

Bladder Outlet Obstruction

Vesicourethral Orifice Obstruction

Bno - [Bladder Neck Obstruction]

Bladder Obstruction Nos

Acquired Bladder Neck Obstruction

Acquired Obstruction Of Bladder Neck Or Vesicourethral Orifice

Bladder Neck Strangulation

Bladder Neck Stricture

Bladder Outflow Obstruction

Contracture Of Bladder Neck Or Sphincter

Contracture Of Bladder Neck

Obstructed Vesicourethral Orifice

Strangulation Of Vesicourethral Orifice

Stricture Of Vesicourethral Orifice

Urinary Prostatic Valve Obstruction

Vesical Obstruction

Juvenile Glaucoma

Glaucoma Of Childhood

Hydrophthalmos

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus GPR180 RGD RGD:1359193
Felis catus GPR180 VGNC VGNC:62690
Mus musculus GPR180 MGD MGI:1930949
Canis familiaris GPR180 VGNC VGNC:41421
Bos taurus GPR180 VGNC VGNC:29575
Macaca mulatta GPR180 VGNC VGNC:103822