1. Gene
  2. TMEM64 - transmembrane protein 64 Gene

TMEM64 - transmembrane protein 64 Gene

中文名称:跨膜蛋白 64

种属: Homo sapiens

基因 ID: 169200 | 基因类型: protein coding

关于 TMEM64

This gene has 7 transcripts (splice variants), 188 orthologues and 2 paralogues. Ubiquitous expression in thyroid (RPKM 12.6), fat (RPKM 10.6) and 25 other tissues.

功能概要

预计参与经典 Wnt 信号通路的负调控;成骨细胞分化的负调节;和脂肪细胞分化的正调节。预计在几个过程的上游或内部起作用,包括骨吸收的正调节;破骨细胞分化的正调节;和 ATP 酶活性的调节。预测位于内质网。预计是膜的组成部分。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to be involved in negative regulation of canonical Wnt signaling pathway; negative regulation of osteoblast differentiation; and positive regulation of fat cell differentiation. Predicted to act upstream of or within several processes, including positive regulation of bone resorption; positive regulation of osteoclast differentiation; and regulation of ATPase activity. Predicted to be located in endoplasmic reticulum. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

TMEM64 基因产物(2)

mRNA Protein Name
NM_001008495.4 NP_001008495.2 transmembrane protein 64 isoform 1
NM_001146273.1 NP_001139745.1 transmembrane protein 64 isoform 2

TMEM64 蛋白结构

SNARE_assoc

SNARE_assoc: SNARE associated Golgi protein (180 - 294)

  • 0
  • 100
  • 200
  • 300
  • 380 a.a.
蛋白主名 其他名称

transmembrane protein 64

关联疾病

疾病名称 别名
Tetraamelia Syndrome

Tetra-Amelia Syndrome

Tetraamelia-Multiple Malformations Syndrome

Tetra-Amelia

Tetra-Amelia, Autosomal Recessive

Tetraamelia, Autosomal Recessive

Total Amelia

Zimmer Phocomelia

Tetams

Zimmer Taub Sova Syndrome

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Canis familiaris TMEM64 VGNC VGNC:54121
Felis catus TMEM64 VGNC VGNC:81680
Mus musculus TMEM64 MGD MGI:2140359
Rattus norvegicus TMEM64 RGD RGD:1596128
Macaca mulatta TMEM64 VGNC VGNC:84127
Bos taurus TMEM64 VGNC VGNC:59370