Mc2r - melanocortin 2 receptor Gene

中文名称：黑皮质素 2 受体

种属: Mus musculus

同用名: ACTHR; MC2-R; ACTH-R

关于 Mc2r

功能概要

预计该基因编码的蛋白可启动 G 蛋白偶联受体活性。预计参与腺苷酸环化酶激活 G 蛋白偶联受体信号通路和代谢过程的调控。预测作用于 G 蛋白偶联受体信号通路的上游或内部。预测位于膜中。预计是膜的组成部分。预计在细胞质和质膜中有活性。以多种结构表达，包括肾上腺；脑;淋巴系统腺体；肺;和生殖系统。该基因与 West 综合征和糖皮质激素缺乏症 1 相关的人类直向同源基因。与人类 MC2R（黑皮质素 2 受体）直向同源基因。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway and regulation of metabolic process. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in cytoplasm and plasma membrane. Is expressed in several structures, including adrenal gland; brain; hemolymphoid system gland; lung; and reproductive system. Human ortholog(s) of this gene implicated in West syndrome and glucocorticoid deficiency 1. Orthologous to human MC2R (melanocortin 2 receptor). [provided by Alliance of Genome Resources, Apr 2022]