Prkcq - protein kinase C, theta Gene

中文名称：蛋白激酶 C, theta

种属: Mus musculus

同用名: Pkcq; PKC-0; PKCtheta; PKC-theta; A130035A12Rik

关于 Prkcq

功能概要

该基因编码的蛋白可启动蛋白激酶 C 活性。参与多个过程，包括 NF-kappaB 转录因子活性的正调控；细胞因子产生的正调节；和细胞间粘附的调节。作用于多个过程的上游或内部，包括 T 细胞增殖的正调节；白介素 2 生成的正向调节；和蛋白质磷酸化。位于细胞质和免疫突触中。以多种结构表达，包括脂肪组织；泌尿生殖系统；直觉;肢;和神经系统。用于研究视网膜脱离。与人 PRKCQ（蛋白激酶 C theta）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables protein kinase C activity. Involved in several processes, including positive regulation of NF-kappaB transcription factor activity; positive regulation of cytokine production; and regulation of cell-cell adhesion. Acts upstream of or within several processes, including positive regulation of T cell proliferation; positive regulation of interleukin-2 production; and protein phosphorylation. Located in cytoplasm and immunological synapse. Is expressed in several structures, including adipose tissue; genitourinary system; gut; limb; and nervous system. Used to study retinal detachment. Orthologous to human PRKCQ (protein kinase C theta). [provided by Alliance of Genome Resources, Apr 2022]