2. Gene
  3. Serpinf2 - serine (or cysteine) peptidase inhibitor, clade F, member 2 Gene

Serpinf2 - serine (or cysteine) peptidase inhibitor, clade F, member 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Pli; Serpimf2

基因 ID: 18816 | 基因类型: protein coding

关于 Serpinf2

功能概要

Predicted to enable protease binding activity; protein homodimerization activity; and serine-type endopeptidase inhibitor activity. Involved in several processes, including collagen fibril organization; maintenance of blood vessel diameter homeostasis by renin-angiotensin; and positive regulation of biosynthetic process. Located in collagen-containing extracellular matrix. Is expressed in several structures, including liver; pancreas epithelium; urinary system; and yolk sac. Used to study alpha-2-plasmin inhibitor deficiency. Human ortholog(s) of this gene implicated in COVID-19 and alpha-2-plasmin inhibitor deficiency. Orthologous to human SERPINF2 (serpin family F member 2). [provided by Alliance of Genome Resources, Apr 2022]

Serpinf2 基因产物(1)

mRNA Protein Name
NM_008878.2 NP_032904.1 alpha-2-antiplasmin precursor
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in blood vessel morphogenesis IMP
IMP: 通过突变表型推断
18436805 MGI
involved in collagen fibril organization IMP
IMP: 通过突变表型推断
17958745 MGI
involved in maintenance of blood vessel diameter homeostasis by renin-angiotensin IMP
IMP: 通过突变表型推断
18436805 MGI
involved in positive regulation of cell differentiation IMP
IMP: 通过突变表型推断
20008146 MGI
involved in positive regulation of collagen biosynthetic process IMP
IMP: 通过突变表型推断
18436805 MGI
involved in positive regulation of smooth muscle cell proliferation IMP
IMP: 通过突变表型推断
18436805 MGI
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
17958745 MGI
involved in positive regulation of transforming growth factor beta production IMP
IMP: 通过突变表型推断
17958745 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

alpha-2-antiplasmin

alpha-2-AP

alpha-2-PI

alpha-2-plasmin inhibitor

pigment epithelium derived factor

plasmin inhibitor alpha 2

serine (or cysteine) proteinase inhibitor, clade F, member 2

serpin F2

重组 Serpinf2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71295 Alpha-2-Antiplasmin/Serpin F2 Protein, Mouse (HEK293, His) Q61247 (V28-K491) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12726 SERPINF2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Serpinf2 NCBI NCBI:5345
Macaca fascicularis Serpinf2 NCBI NCBI:102116557
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