EIF4EBP2 - eukaryotic translation initiation factor 4E binding protein 2 Gene

中文名称：真核翻译起始因子 4E 结合蛋白 2

种属: Homo sapiens

同用名: 4EBP2; PHASII

关于 EIF4EBP2

功能概要

该基因编码真核翻译起始因子 4E 结合蛋白家族的成员。该家族的基因产物结合 eIF4E 并抑制翻译起始。然而，胰岛素和其他生长因子可以通过磷酸化依赖性破坏它们与 eIF4E 的结合来释放这种抑制作用。通过这些基因产物调节蛋白质生产与细胞增殖、细胞分化和病毒感染有关。[RefSeq 提供，2008 年 10 月]

This gene encodes a member of the eukaryotic translation initiation factor 4E binding protein family. The gene products of this family bind eIF4E and inhibit translation initiation. However, Insulin and Other growth factors can release this inhibition via a phosphorylation-dependent disruption of their binding to eIF4E. Regulation of protein production through these gene products have been implicated in cell proliferation, cell differentiation and viral Infection. [provided by RefSeq, Oct 2008]