2. Gene
  3. NRK - Nik related kinase Gene

NRK - Nik related kinase Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：Nik 相关激酶

种属: Homo sapiens

同用名: NESK

基因 ID: 203447 | 基因类型: protein coding

关于 NRK

Cytogenetic location: Xq22.3 Genomic coordinates (GRCh38): X:105,821,786-105,958,610 (from NCBI)

This gene has 4 transcripts (splice variants), 96 orthologues and 35 paralogues. Biased expression in ovary (RPKM 15.5), placenta (RPKM 15.0) and 8 other tissues.

功能概要

该基因的小鼠直系同源物编码 JNK 激活所需的蛋白激酶。编码的蛋白质可能参与晚期胚胎发生中肌动蛋白聚合的诱导。[RefSeq 提供，2010 年 6 月]

The mouse ortholog of this gene encodes a protein kinase required for JNK activation. The encoded protein may be involved in the induction of actin polymerization in late embryogenesis.[provided by RefSeq, Jun 2010]

NRK 基因产物(1)

mRNA Protein Name
NM_198465.4 NP_940867.2 nik-related protein kinase

NRK 蛋白结构

Pkinase

Pkinase: Protein kinase domain (26 - 313)

CNH

CNH: CNH domain (1213 - 1548)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1582 a.a.
蛋白主名 其他名称

nik-related protein kinase

关联疾病

疾病名称 别名
Hypermobility Syndrome

Benign Joint Hypermobility
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-146434 TGFβ-IN-2 Inhibitor 99.37% 否
HY-147716 CDK8-IN-6 Inhibitor / 否
HY-147717 CDK8-IN-7 Inhibitor / 否
HY-168860 Antituberculosis agent-13 Inhibitor / 否
HY-170540 NOX4-IN-1 Inhibitor / 否
HY-RS09574 NRK Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS16266 NRK Mouse Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus NRK VGNC VGNC:97537
Rattus norvegicus NRK RGD RGD:1566163
Canis familiaris NRK VGNC VGNC:43971
Mus musculus NRK MGD MGI:1351326
Macaca mulatta NRK VGNC VGNC:81488
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