2. Gene
  3. Tgm2 - transglutaminase 2, C polypeptide Gene

Tgm2 - transglutaminase 2, C polypeptide Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: TG2; tTG; G[a]h; tTGas; TGase2

基因 ID: 21817 | 基因类型: protein coding

关于 Tgm2

功能概要

Enables protein-glutamine gamma-glutamyltransferase activity. Involved in cellular calcium ion homeostasis; positive regulation of cell adhesion; and regulation of apoptotic cell clearance. Acts upstream of or within branching involved in salivary gland morphogenesis and salivary gland cavitation. Located in collagen-containing extracellular matrix. Is expressed in several structures, including alimentary system; central nervous system; cranium; genitourinary system; and sensory organ. Used to study maturity-onset diabetes of the young. Orthologous to human TGM2 (transglutaminase 2). [provided by Alliance of Genome Resources, Apr 2022]

Tgm2 基因产物(1)

mRNA Protein Name
NM_009373.3 NP_033399.1 protein-glutamine gamma-glutamyltransferase 2
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein-glutamine gamma-glutamyltransferase activity IMP
IMP: 通过突变表型推断
11113189 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within branching involved in salivary gland morphogenesis IMP
IMP: 通过突变表型推断
15970210 MGI
involved in negative regulation of endoplasmic reticulum calcium ion concentration IMP
IMP: 通过突变表型推断
24349085 MGI
involved in positive regulation of cell adhesion IMP
IMP: 通过突变表型推断
11274171 MGI
involved in positive regulation of mitochondrial calcium ion concentration IMP
IMP: 通过突变表型推断
24349085 MGI
involved in regulation of apoptotic cell clearance IMP
IMP: 通过突变表型推断
12810961 MGI
acts upstream of or within salivary gland cavitation IMP
IMP: 通过突变表型推断
15970210 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

protein-glutamine gamma-glutamyltransferase 2

C polypeptide

TG(C)

TGC

TGase C

TGase II

TGase-2

isopeptidase TGM2

protein-glutamine deamidase TGM2

protein-glutamine dopaminyltransferase TGM2

protein-glutamine histaminyltransferase TGM2

protein-glutamine noradrenalinyltransferase TGM2

protei

重组 Tgm2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71132 TGM2/Transglutaminase 2 Protein, Mouse (HEK293, His) P21981 (A2-A686) ≥95%
HY-P78361 TGM2/Transglutaminase 2 Protein, Mouse (His) P21981 (A2-A686) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-117678 TG-2-IN-1 Inhibitor ≥98.0% 否
HY-12589 ZM39923 hydrochloride Inhibitor 98.19% 否
HY-RS14459 TGM2 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-12589A ZM39923 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tgm2 NCBI NCBI:7052
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