2. Gene
  3. HS3ST5 - heparan sulfate-glucosamine 3-sulfotransferase 5 Gene

HS3ST5 - heparan sulfate-glucosamine 3-sulfotransferase 5 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：硫酸乙酰肝素-氨基葡萄糖 3-磺基转移酶 5

种属: Homo sapiens

同用名: 3OST5; 3-OST-5; HS3OST5; NBLA04021

基因 ID: 222537 | 基因类型: protein coding

关于 HS3ST5

Cytogenetic location: 6q21-q22.1 Genomic coordinates (GRCh38): 6:114,055,596-114,343,023 (from NCBI)

This gene has 2 transcripts (splice variants), 196 orthologues and 10 paralogues. Low expression observed in reference dataset.

功能概要

HS3ST5 属于一组硫酸乙酰肝素 3-O-磺基转移酶 (EC 2.8.2.23) ，可将硫酸盐从 3-磷酸腺苷 5-磷酸磷酸盐 (PAPS) 转移到硫酸乙酰肝素和肝素 (Mochizuki 等人，2003 [PubMed 12740361) ]) .[OMIM 提供，2008 年 3 月]

HS3ST5 belongs to a group of heparan sulfate 3-O-sulfotransferases (EC 2.8.2.23) that transfer sulfate from 3-prime-phosphoadenosine 5-prime phosphosulfate (PAPS) to heparan sulfate and heparin (Mochizuki et al., 2003 [PubMed 12740361]).[supplied by OMIM, Mar 2008]

HS3ST5 基因产物(10)

mRNA Protein Name
NM_001387039.1 NP_001373968.1 heparan sulfate glucosamine 3-O-sulfotransferase 5
NM_001387040.1 NP_001373969.1 heparan sulfate glucosamine 3-O-sulfotransferase 5
NM_001387041.1 NP_001373970.1 heparan sulfate glucosamine 3-O-sulfotransferase 5
NM_001387042.1 NP_001373971.1 heparan sulfate glucosamine 3-O-sulfotransferase 5
NM_001387043.1 NP_001373972.1 heparan sulfate glucosamine 3-O-sulfotransferase 5
NM_001387044.1 NP_001373973.1 heparan sulfate glucosamine 3-O-sulfotransferase 5
NM_001387045.1 NP_001373974.1 heparan sulfate glucosamine 3-O-sulfotransferase 5
NM_001387046.1 NP_001373975.1 heparan sulfate glucosamine 3-O-sulfotransferase 5
NM_001387047.1 NP_001373976.1 heparan sulfate glucosamine 3-O-sulfotransferase 5
NM_153612.4 NP_705840.2 heparan sulfate glucosamine 3-O-sulfotransferase 5

HS3ST5 蛋白结构

Sulfotransfer_1

Sulfotransfer_1: Sulfotransferase domain (91 - 335)

  • 0
  • 100
  • 200
  • 300
  • 346 a.a.
蛋白主名 其他名称

heparan sulfate glucosamine 3-O-sulfotransferase 5

h3-OST-5

关联疾病

疾病名称 别名
Breast Pericanalicular Fibroadenoma

Pericanalicular Fibroadenoma

Pericanalicular Fibroadenoma Of Breast
Syndromic X-Linked Intellectual Disability Najm Type

Mental Retardation And Microcephaly With Pontine And Cerebellar Hypoplasia

Micpch

X-Linked Intellectual Disability-Microcephaly-Pontocerebellar Hypoplasia Syndrome
Omodysplasia

Omodysplasia Type 1

Omodysplasia 2
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06381 HS3ST5 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus HS3ST5 RGD RGD:1306379
Macaca mulatta HS3ST5 VGNC VGNC:104404
Bos taurus HS3ST5 VGNC VGNC:29960
Canis familiaris HS3ST5 VGNC VGNC:41793
Mus musculus HS3ST5 MGD MGI:2441996
Felis catus HS3ST5 VGNC VGNC:62843
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