2. Gene
  3. LAMB4 - laminin subunit beta 4 Gene

LAMB4 - laminin subunit beta 4 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品

中文名称：层粘连蛋白亚基β4

种属: Homo sapiens

基因 ID: 22798 | 基因类型: protein coding

关于 LAMB4

Cytogenetic location: 7q31.1 Genomic coordinates (GRCh38): 7:108,011,662-108,130,361 (from NCBI)

This gene has 8 transcripts (splice variants), 128 orthologues and 27 paralogues. Biased expression in skin (RPKM 11.6), placenta (RPKM 1.2) and 1 other tissue.

功能概要

预测为细胞外基质结构成分。预计参与多个过程，包括基底膜组装；细胞迁移；和底物粘附依赖性细胞扩散。预测位于基底膜；胞外区；和膜。预计是层粘连蛋白复合物的一部分。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to be an extracellular matrix structural constituent. Predicted to be involved in several processes, including basement membrane assembly; cell migration; and substrate adhesion-dependent cell spreading. Predicted to be located in basement membrane; extracellular region; and membrane. Predicted to be part of laminin complex. [provided by Alliance of Genome Resources, Apr 2022]

LAMB4 基因产物(4)

mRNA Protein Name
NM_001318046.2 NP_001304975.1 laminin subunit beta-4 isoform 1 precursor
NM_001318047.2 NP_001304976.1 laminin subunit beta-4 isoform 2 precursor
NM_001318048.2 NP_001304977.1 laminin subunit beta-4 isoform 3 precursor
NM_007356.3 NP_031382.2 laminin subunit beta-4 isoform 1 precursor

LAMB4 蛋白结构

Laminin_N

Laminin_N: Laminin N-terminal (Domain VI) (28 - 263)

Laminin_EGF

Laminin_EGF: Laminin EGF domain (265 - 320)

Laminin_EGF

Laminin_EGF: Laminin EGF domain (332 - 383)

Laminin_EGF

Laminin_EGF: Laminin EGF domain (395 - 452)

Laminin_EGF

Laminin_EGF: Laminin EGF domain (455 - 503)

Laminin_EGF

Laminin_EGF: Laminin EGF domain (506 - 544)

Laminin_EGF

Laminin_EGF: Laminin EGF domain (769 - 814)

Laminin_EGF

Laminin_EGF: Laminin EGF domain (817 - 865)

Laminin_EGF

Laminin_EGF: Laminin EGF domain (911 - 967)

Laminin_EGF

Laminin_EGF: Laminin EGF domain (970 - 1019)

Laminin_EGF

Laminin_EGF: Laminin EGF domain (1022 - 1077)

Laminin_EGF

Laminin_EGF: Laminin EGF domain (1080 - 1121)

Laminin_EGF

Laminin_EGF: Laminin EGF domain (1128 - 1168)

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  • 1761 a.a.
蛋白主名 其他名称

laminin subunit beta-4

laminin beta-1-related protein

关联疾病

疾病名称 别名
Diverticulitis
Diverticulitis Of Colon

Colonic Diverticular Disease

Diverticulitis, Colonic

Diverticular Disease Of Colon
Macular Degeneration, Age-Related, 13

Age Related Macular Degeneration 13

ARMD13

Macular Degeneration, Age-Related, 13, Susceptibility To

Macular Degeneration, Age-Related, Type 13
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07505 LAMB4 Human Pre-designed siRNA Set A Pre-designed Sets / 否
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