2. Gene
  3. HSPA4L - heat shock protein family A (Hsp70) member 4 like Gene

HSPA4L - heat shock protein family A (Hsp70) member 4 like Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：热休克蛋白家族 A (Hsp70) 成员 4

种属: Homo sapiens

同用名: APG1; APG-1; HSPH3; Osp94

基因 ID: 22824 | 基因类型: protein coding

关于 HSPA4L

Cytogenetic location: 4q28.1 Genomic coordinates (GRCh38): 4:127,781,796-127,840,733 (from NCBI)

This gene has 5 transcripts (splice variants), 217 orthologues and 13 paralogues. Biased expression in testis (RPKM 41.4), esophagus (RPKM 5.8) and 4 other tissues.

功能概要

该基因编码的蛋白质可诱导热休克，可作为伴侣。编码的蛋白质可以保护热休克细胞免受聚集蛋白质的有害影响。该基因在白血病细胞中高度表达，可能是治疗干预的良好靶标。已发现该基因编码不同亚型的几种转录本。[RefSeq 提供，2015 年 12 月]

The protein encoded by this gene is heat shock inducible and may act as a chaperone. The encoded protein can protect the heat-shocked cell against the harmful effects of aggregated proteins. This gene is highly expressed in leukemia cells and may be a good target for therapeutic intervention. Several transcripts encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]

HSPA4L 基因产物(4)

mRNA Protein Name
NM_001317381.2 NP_001304310.1 heat shock 70 kDa protein 4L isoform 2
NM_001317382.2 NP_001304311.1 heat shock 70 kDa protein 4L isoform 3
NM_001317383.2 NP_001304312.1 heat shock 70 kDa protein 4L isoform 4
NM_014278.4 NP_055093.2 heat shock 70 kDa protein 4L isoform 1

HSPA4L 蛋白结构

HSP70

HSP70: Hsp70 protein (3 - 579)

HSP70

HSP70: Hsp70 protein (593 - 693)

  • 0
  • 200
  • 400
  • 600
  • 839 a.a.
蛋白主名 其他名称

heat shock 70 kDa protein 4L

HSPA4-like protein

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06431 HSPA4L Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus HSPA4L MGD MGI:107422
Felis catus HSPA4L VGNC VGNC:78511
Bos taurus HSPA4L VGNC VGNC:53906
Macaca mulatta HSPA4L VGNC VGNC:100236
Rattus norvegicus HSPA4L RGD RGD:1306528
Canis familiaris HSPA4L VGNC VGNC:54806
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