Pde11a - phosphodiesterase 11A Gene

中文名称：磷酸二酯酶 11A

种属: Mus musculus

同用名: Gm350; PDE11A1; 6330414F14Rik; A630086N24Rik

关于 Pde11a

功能概要

预测该基因编码的蛋白可实现 cGMP 结合活性和 cGMP 刺激的环核苷酸磷酸二酯酶活性。预计参与 cAMP 介导信号的负调控； cGMP 介导的信号负调节；和信号转导。预测位于核周。在中轴骨骼和神经系统中表达。该基因的人类直系同源物与原发性色素性结节性肾上腺皮质疾病有关。与人 PDE11A（磷酸二酯酶 11A）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable cGMP binding activity and cGMP-stimulated cyclic-nucleotide phosphodiesterase activity. Predicted to be involved in negative regulation of cAMP-mediated signaling; negative regulation of cGMP-mediated signaling; and signal transduction. Predicted to be located in perikaryon. Is expressed in axial skeleton and nervous system. Human ortholog(s) of this gene implicated in primary pigmented nodular adrenocortical disease. Orthologous to human PDE11A (phosphodiesterase 11A). [provided by Alliance of Genome Resources, Apr 2022]