2. Gene
  3. P2rx6 - purinergic receptor P2X 6 Gene

P2rx6 - purinergic receptor P2X 6 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: P2x6; P2rxl1; Rnap2x6

基因 ID: 25041 | 基因类型: protein coding

关于 P2rx6

功能概要

Enables extracellularly ATP-gated cation channel activity. Predicted to be involved in cation transmembrane transport; cell surface receptor signaling pathway; and response to ATP. Located in several cellular components, including dendritic spine; neuronal cell body; and postsynaptic density. Is active in glutamatergic synapse and parallel fiber to Purkinje cell synapse. Is integral component of postsynaptic specialization membrane. Orthologous to human P2RX6 (purinergic receptor P2X 6). [provided by Alliance of Genome Resources, Apr 2022]

P2rx6 基因产物(1)

mRNA Protein Name
NM_012721.2 NP_036853.2 P2X purinoceptor 6
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables extracellularly ATP-gated monoatomic cation channel activity IDA
IDA: 通过直接分析推断
8786426 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
24815693 RGD
enables protein-containing complex binding IDA
IDA: 通过直接分析推断
17449665 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in dendritic spine IDA
IDA: 通过直接分析推断
11160443 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
11160443 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
11160443 RGD
is active in parallel fiber to Purkinje cell synapse IDA
IDA: 通过直接分析推断
11160443 RGD
is active in postsynaptic specialization membrane IDA
IDA: 通过直接分析推断
11160443 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

P2X purinoceptor 6

ATP receptor

P2X6 receptor

P2XM

purinergic receptor P2X, ligand-gated ion channel, 6

purinergic receptor P2X-like 1 orphan receptor

purinergic receptor P2X6

P2rx6 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
P2rx6 P51579 P2rx2 Rattus norvegicus P49653
IF
24815693
种属内
P2rx6 P51579 P2rx2 Rattus norvegicus P49653
Anti Tag CoIP
24815693
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09910 P2RX6 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens P2rx6 NCBI NCBI:9127
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