2. Gene
  3. ABI3BP - ABI family member 3 binding protein Gene

ABI3BP - ABI family member 3 binding protein Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：ABI 家族成员 3 结合蛋白

种属: Homo sapiens

同用名: TARSH; NESHBP

基因 ID: 25890 | 基因类型: protein coding

关于 ABI3BP

Cytogenetic location: 3q12.2 Genomic coordinates (GRCh38): 3:100,749,156-100,993,421 (from NCBI)

This gene has 28 transcripts (splice variants), 268 orthologues and 1 paralogue. Broad expression in gall bladder (RPKM 33.8), lung (RPKM 26.2) and 21 other tissues.

功能概要

预测启用肌动蛋白丝结合活性和糖胺聚糖结合活性。预计参与肌动蛋白细胞骨架重组的调控；树突棘形态发生的调节；和突触后密度组装的调节。预计在细胞外基质组织的上游或细胞外基质组织内起作用，并积极调节细胞-基质粘附。位于细胞外空间。与含胶原蛋白的细胞外基质共定位。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable actin filament binding activity and glycosaminoglycan binding activity. Predicted to be involved in regulation of actin Cytoskeleton reorganization; regulation of dendritic spine morphogenesis; and regulation of postsynaptic density assembly. Predicted to act upstream of or within extracellular matrix organization and positive regulation of cell-substrate adhesion. Located in extracellular space. Colocalizes with collagen-containing extracellular matrix. [provided by Alliance of Genome Resources, Apr 2022]

ABI3BP 基因产物(11)

mRNA Protein Name
NM_001349329.2 NP_001336258.2 target of Nesh-SH3 isoform 1 precursor
NM_001349330.2 NP_001336259.2 target of Nesh-SH3 isoform 2 precursor
NM_001349331.2 NP_001336260.2 target of Nesh-SH3 isoform 3 precursor
NM_001349332.2 NP_001336261.2 target of Nesh-SH3 isoform 4 precursor
NM_001365642.2 NP_001352571.2 target of Nesh-SH3 isoform 6 precursor
NM_001365643.2 NP_001352572.2 target of Nesh-SH3 isoform 7 precursor
NM_001375547.2 NP_001362476.1 target of Nesh-SH3 isoform 8 precursor
NM_001375549.2 NP_001362478.1 target of Nesh-SH3 isoform 9 precursor
NM_001375550.1 NP_001362479.1 target of Nesh-SH3 isoform 10 precursor
NM_001377332.1 NP_001364261.1 target of Nesh-SH3 isoform 11 precursor
NM_015429.4 NP_056244.3 target of Nesh-SH3 isoform 5 precursor

ABI3BP 蛋白结构

fn3

fn3: Fibronectin type III domain (840 - 921)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 1000
  • 1075 a.a.
蛋白主名 其他名称

target of Nesh-SH3

ABI family, member 3 (NESH) binding protein

关联疾病

疾病名称 别名
Benign Pleural Mesothelioma

Mesothelioma Of Pleura

Benign Neoplasm Of Mesothelial Tissue Of Pleura

Pleural Malignant Mesothelioma
Agnathia-Otocephaly Complex

Otocephaly

Holoprosencephaly-Agnathia

Dysgnathia Complex Agnathia-Holoprosencephaly

AGOTC

Agnathia-Holoprosencephaly-Situs Inversus Syndrome

Dysgnathia Complex

Agnathia-Holoprosencephaly

Cervical Auricle
Fibrochondrogenesis

Fbcg1

Fbcg2

Fibrochondrogenesis-1

Fibrochondrogenesis-2

Fibrochondrogenesis 1

Fibrochondrogenesis 2
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00101 ABI3BP Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris ABI3BP VGNC VGNC:37477
Felis catus ABI3BP VGNC VGNC:59489
Rattus norvegicus ABI3BP RGD RGD:1562717
Macaca mulatta ABI3BP VGNC VGNC:81175
Mus musculus ABI3BP MGD MGI:2444583
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z