1. Gene
  2. HS6ST3 - heparan sulfate 6-O-sulfotransferase 3 Gene

HS6ST3 - heparan sulfate 6-O-sulfotransferase 3 Gene

中文名称:硫酸乙酰肝素 6-O-磺基转移酶 3

种属: Homo sapiens

同用名: HS6ST-3

基因 ID: 266722 | 基因类型: protein coding

关于 HS6ST3

Cytogenetic location: 13q32.1 Genomic coordinates (GRCh38): 13:96,090,107-96,839,562 (from NCBI)

This gene has 2 transcripts (splice variants), 275 orthologues and 2 paralogues. Biased expression in brain (RPKM 5.5), urinary bladder (RPKM 1.6) and 3 other tissues.

功能概要

硫酸乙酰肝素 (HS) 磺基转移酶,如 HS6ST3,修饰 HS 以生成 HS 与多种蛋白质相互作用所需的结构。这些相互作用涉及增殖和分化、粘附、迁移、炎症、血液凝固和其他不同过程 (Habuchi 等人,2000 [PubMed 10644753]) 。[OMIM 提供,2008 年 3 月]

Heparan sulfate (HS) sulfotransferases, such as HS6ST3, modify HS to generate structures required for interactions between HS and a variety of proteins. These interactions are implicated in proliferation and differentiation, adhesion, migration, inflammation, blood coagulation, and other diverse processes (Habuchi et al., 2000 [PubMed 10644753]).[supplied by OMIM, Mar 2008]

HS6ST3 基因产物(1)

mRNA Protein Name
NM_153456.4 NP_703157.2 heparan-sulfate 6-O-sulfotransferase 3 precursor

HS6ST3 蛋白结构

Sulfotransfer_2

Sulfotransfer_2: Sulfotransferase family (139 - 411)

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  • 471 a.a.
蛋白主名 其他名称

heparan-sulfate 6-O-sulfotransferase 3

直系同源

种属 基因名 来源 基因 ID
Mus musculus HS6ST3 MGD MGI:1354960
Bos taurus HS6ST3 VGNC VGNC:106775
Rattus norvegicus HS6ST3 RGD RGD:1305888
Felis catus HS6ST3 VGNC VGNC:102226
Macaca mulatta HS6ST3 VGNC VGNC:84889