2. Gene
  3. RGL4 - ral guanine nucleotide dissociation stimulator like 4 Gene

RGL4 - ral guanine nucleotide dissociation stimulator like 4 Gene

  • 基因
  • 蛋白
  • 相关产品

中文名称：ral 鸟嘌呤核苷酸解离刺激物样 4

种属: Homo sapiens

同用名: Rgr

基因 ID: 266747 | 基因类型: protein coding

关于 RGL4

Cytogenetic location: 22q11.23 Genomic coordinates (GRCh38): 22:23,691,013-23,699,168 (from NCBI)

This gene has 10 transcripts (splice variants), 22 orthologues and 24 paralogues. Ubiquitous expression in bone marrow (RPKM 20.9), appendix (RPKM 6.7) and 23 other tissues.

功能概要

这种致癌基因编码的蛋白质类似于鸟嘌呤核苷酸交换因子 Ral 鸟嘌呤解离刺激物。该基因表达的增加导致编码的蛋白质易位至细胞膜。编码的蛋白质可以激活多种途径，包括 Ras-Raf-MEK-ERK 级联。[RefSeq 提供，2016 年 7 月]

This oncogene encodes a protein similar to guanine nucleotide exchange factor Ral guanine dissociation stimulator. Increased expression of this gene leads to translocation of the encoded protein to the cell membrane. The encoded protein can activate several pathways, including the Ras-Raf-MEK-ERK cascade. [provided by RefSeq, Jul 2016]

RGL4 基因产物(3)

mRNA Protein Name
NM_001329424.3 NP_001316353.1 ral-GDS-related protein isoform 1 precursor
NM_001329425.2 NP_001316354.1 ral-GDS-related protein isoform 3
NM_153615.2 NP_705843.1 ral-GDS-related protein isoform 2 precursor

RGL4 蛋白结构

RasGEF

RasGEF: RasGEF domain (217 - 420)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 473 a.a.
蛋白主名 其他名称

ral-GDS-related protein

Ral-GDS related protein Rgr

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11893 RGL4 Human Pre-designed siRNA Set A Pre-designed Sets / 否
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