1. Gene
  2. Brpf3 - bromodomain and PHD finger containing, 3 Gene

Brpf3 - bromodomain and PHD finger containing, 3 Gene

中文名称:含溴结构域和 PHD 指,3

种属: Mus musculus

同用名: mKIAA1286

基因 ID: 268936 | 基因类型: protein coding

关于 Brpf3

Chromosome 17: 29,020,064-29,058,923 forward strand.GRCm39:CM001010.3

This gene has 19 transcripts (splice variants), 287 orthologues, 8 paralogues and is associated with 2 phenotypes. Ubiquitous expression in liver E14.5 (RPKM 22.7), liver E14 (RPKM 19.6) and 28 other tissues.

功能概要

预测该基因编码的蛋白可启动组蛋白结合活性。预计参与组蛋白 H3-K14 乙酰化和 DNA 复制的正调控。预测作用于染色质组织的上游或内部。预测位于核内。预计是 MOZ/MORF 组蛋白乙酰转移酶复合物的一部分。以多种结构表达,包括胚外成分;泌尿生殖系统;直觉;感觉器官;和骨架。与人类 BRPF3 同源(含溴结构域和 PHD 指 3)。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable histone binding activity. Predicted to be involved in histone H3-K14 acetylation and positive regulation of DNA replication. Predicted to act upstream of or within chromatin organization. Predicted to be located in nucleus. Predicted to be part of MOZ/MORF Histone Acetyltransferase complex. Is expressed in several structures, including extraembryonic component; genitourinary system; gut; sensory organ; and skeleton. Orthologous to human BRPF3 (bromodomain and PHD finger containing 3). [provided by Alliance of Genome Resources, Apr 2022]

Brpf3 基因产物(1)

mRNA Protein Name
NM_001081315.1 NP_001074784.1 bromodomain and PHD finger-containing protein 3

Brpf3 蛋白结构

COG5141

COG5141: cl34917 (116 - 602)

ePHD_BRPF3

ePHD_BRPF3: cd15703 (268 - 385)

Bromo_brd1_like

Bromo_brd1_like: cd05512 (591 - 688)

PWWP_BRPF3

PWWP_BRPF3: cd20158 (1072 - 1189)

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  • 1204 a.a.
蛋白主名 其他名称

bromodomain and PHD finger-containing protein 3

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Brpf3 NCBI NCBI:27154