2. Gene
  3. IL17B - interleukin 17B Gene

IL17B - interleukin 17B Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：白细胞介素 17B

种属: Homo sapiens

同用名: NIRF; IL-20; IL-17B; ZCYTO7

基因 ID: 27190 | 基因类型: protein coding

关于 IL17B

Cytogenetic location: 5q32 Genomic coordinates (GRCh38): 5:149,374,267-149,404,202 (from NCBI)

This gene has 3 transcripts (splice variants), 137 orthologues and 5 paralogues. Low expression observed in reference dataset.

功能概要

该基因编码的蛋白质是一种 T 细胞衍生的细胞因子，与 IL17 具有序列相似性。据报道，该细胞因子可刺激单核细胞系释放 TNF α (TNF) 和 IL1 β (IL1B) 。几种神经组织的免疫组织化学分析表明，这种细胞因子主要定位于神经元细胞体。可变剪接导致多个剪接变体。[RefSeq 提供，2015 年 12 月]

The protein encoded by this gene is a T cell-derived cytokine that shares sequence similarity with IL17. This cytokine was reported to stimulate the release of TNF alpha (TNF) and IL1 beta (IL1B) from a monocytic cell line. Immunohistochemical analysis of several nerve tissues indicated that this cytokine is primarily localized to neuronal cell bodies. Alternative splicing results in multiple splice variants. [provided by RefSeq, Dec 2015]

IL17B 基因产物(2)

mRNA Protein Name
NM_001317987.2 NP_001304916.1 interleukin-17B isoform 2
NM_014443.3 NP_055258.1 interleukin-17B isoform 1 precursor

IL17B 蛋白结构

IL17

IL17: Interleukin-17 (95 - 180)

  • 0
  • 100
  • 180 a.a.
蛋白主名 其他名称

interleukin-17B

cytokine-like protein ZCYTO7

重组 IL17B 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72588 IL-17B Protein, Human (HEK293, Fc) Q9UHF5 (Q21-F180) ≥95%
HY-P700105AF Animal-Free IL-17B Protein, Human (His) Q9UHF5 (Q21-F180) ≥95%

关联疾病

疾病名称 别名
Leiomyoma

Leiomyomatous Neoplasm

Leiomyomatous Tumor

Leiomyomas

Fibroid Tumor

Uterine Fibroids
Psoriasis
Rheumatoid Arthritis

RA

Arthritis, Rheumatoid

Rheumatoid Arthritis, Susceptibility To

Arthritis Or Polyarthritis, Rheumatic

Atrophic Arthritis

Rheumatism Arthritis

Rheumatoid Polyarthritis
Systemic Lupus Erythematosus

Lupus Nephritis

SLE

Disseminated Lupus Erythematosus

Systemic Lupus Erythematosus, Susceptibility To

Lupus Erythematosus, Systemic

Lupus Nephritis, Susceptibility To

Libman-Sacks Disease

Systemic Lupus Erythematosus Susceptibility To

Sle - Lupus Erythematosus, Systemic

Le Syndrome

Lupus

Lupus Erythematosus Systemic

Lupus Erythematosus, Systemic, Susceptibility To

Lupus Vulgaris

Lupus Erythematosus, Discoid

Lupus Erythematosus

Systemic Lupus Erythematosus Nos

Sle - [Systemic Lupus Erythematosus]
Chronic Mucocutaneous Candidiasis

Candidiasis, Chronic Mucocutaneous

Cmc

Candidiasis Chronic Mucocutaneous
Charcot-Marie-Tooth Disease

Cmt

Hmsn

Hereditary Motor And Sensory Neuropathy

Pma

Cmt - Charcot-Marie-Tooth Disease

Charcot Marie Tooth Disease

Charcot-Marie-Tooth Hereditary Neuropathy

Charcot-Marie-Tooth Syndrome

Peroneal Muscular Atrophy

Hereditary Motor And Sensory Neuropathies
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06698 IL17B Human Pre-designed siRNA Set A Pre-designed Sets / 否
抗体抑制剂 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P990741 Galvokimig / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus IL17B VGNC VGNC:102232
Canis familiaris IL17B VGNC VGNC:41943
Bos taurus IL17B VGNC VGNC:30118
Mus musculus IL17B MGD MGI:1928397
Macaca mulatta IL17B VGNC VGNC:110458
Rattus norvegicus IL17B RGD RGD:620614
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