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  2. ADAMDEC1 - ADAM like decysin 1 Gene

ADAMDEC1 - ADAM like decysin 1 Gene

中文名称:ADAM 样 decysin 1

种属: Homo sapiens

同用名: M12.219

基因 ID: 27299 | 基因类型: protein coding

关于 ADAMDEC1

Cytogenetic location: 8p21.2 Genomic coordinates (GRCh38): 8:24,384,285-24,406,013 (from NCBI)

This gene has 4 transcripts (splice variants), 358 orthologues and 20 paralogues. Biased expression in small intestine (RPKM 233.3), colon (RPKM 104.6) and 4 other tissues.

功能概要

这种编码的蛋白质被认为是属于去整合素金属蛋白酶家族的分泌蛋白。其表达在树突细胞成熟过程中上调。这种蛋白质可能在树突状细胞功能及其与生发中心 T 细胞的相互作用中发挥重要作用。[RefSeq 提供,2008 年 7 月]

This encoded protein is thought to be a secreted protein belonging to the disintegrin metalloproteinase family. Its expression is upregulated during dendritic cells maturation. This protein may play an important role in dendritic cell function and their interactions with germinal center T cells. [provided by RefSeq, Jul 2008]

ADAMDEC1 基因产物(3)

mRNA Protein Name
NM_001145271.2 NP_001138743.1 ADAM 1-Dec isoform 2
NM_001145272.2 NP_001138744.1 ADAM 1-Dec isoform 2
NM_014479.3 NP_055294.1 ADAM 1-Dec isoform 1 precursor

ADAMDEC1 蛋白结构

Pep_M12B_propep

Pep_M12B_propep: Reprolysin family propeptide (43 - 173)

Reprolysin

Reprolysin: Reprolysin (M12B) family zinc metalloprotease (218 - 412)

Disintegrin

Disintegrin: Disintegrin (429 - 461)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 470 a.a.
蛋白主名 其他名称

ADAM DEC1

ADAM-like protein decysin-1

重组 ADAMDEC1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7460 ADAMDEC1 Protein, Human (HEK293, His) O15204 (K206-E470) ≥95%

关联疾病

疾病名称 别名
Rosacea

Erythematotelangiectatic Rosacea

Papulopustular Rosacea

Phymatous Rosacea

Acne Roscea

Acne, Erythematosa

Granulomatous Rosacea

Ocular Rosacea

Acne Rosacea

Hypertrophic Rosacea

Inflammatory Bowel Disease

Inflammatory Bowel Diseases

Bowel Disease, Inflammatory

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta ADAMDEC1 VGNC VGNC:69422
Canis familiaris ADAMDEC1 VGNC VGNC:37589
Felis catus ADAMDEC1 VGNC VGNC:59586
Mus musculus ADAMDEC1 MGD MGI:1917650
Rattus norvegicus ADAMDEC1 RGD RGD:1309861
Others ADAMDEC1 NCBI