1. Gene
  2. CD163L1 - CD163 molecule like 1 Gene

CD163L1 - CD163 molecule like 1 Gene

中文名称:CD163 分子样 1

种属: Homo sapiens

同用名: WC1; M160; STAR; CD163B; SCARI2

基因 ID: 283316 | 基因类型: protein coding

关于 CD163L1

Cytogenetic location: 12p13.31 Genomic coordinates (GRCh38): 12:7,318,768-7,444,153 (from NCBI)

This gene has 10 transcripts (splice variants), 1193 orthologues and 15 paralogues. Broad expression in spleen (RPKM 7.7), small intestine (RPKM 4.5) and 14 other tissues.

功能概要

该基因编码清道夫受体富含半胱氨酸 (SRCR) 超家族的成员。该家族的成员是分泌型或膜锚定蛋白,主要存在于与免疫系统相关的细胞中。 SRCR 家族由 100-110 个氨基酸的 SRCR 结构域定义,可介导蛋白质-蛋白质相互作用和配体结合。编码的蛋白质包含十二个 SRCR 结构域、一个跨膜区和一个细胞质结构域。可变剪接导致编码不同异构体的多个转录变体。[RefSeq 提供,2014 年 7 月]

This gene encodes a member of the scavenger receptor cysteine-rich (SRCR) superfamily. Members of this family are secreted or membrane-anchored proteins mainly found in cells associated with the immune system. The SRCR family is defined by a 100-110 amino acid SRCR domain, which may mediate protein-protein interaction and ligand binding. The encoded protein contains twelve SRCR domains, a transmembrane region and a cytoplasmic domain. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]

CD163L1 基因产物(2)

mRNA Protein Name
NM_001297650.2 NP_001284579.2 scavenger receptor cysteine-rich type 1 protein M160 isoform 1 precursor
NM_174941.6 NP_777601.3 scavenger receptor cysteine-rich type 1 protein M160 isoform 2 precursor

CD163L1 蛋白结构

SRCR

SRCR: Scavenger receptor cysteine-rich domain (51 - 147)

SRCR

SRCR: Scavenger receptor cysteine-rich domain (158 - 254)

SRCR

SRCR: Scavenger receptor cysteine-rich domain (265 - 362)

SRCR

SRCR: Scavenger receptor cysteine-rich domain (373 - 469)

SRCR

SRCR: Scavenger receptor cysteine-rich domain (479 - 576)

SRCR

SRCR: Scavenger receptor cysteine-rich domain (586 - 683)

SRCR

SRCR: Scavenger receptor cysteine-rich domain (693 - 790)

SRCR

SRCR: Scavenger receptor cysteine-rich domain (799 - 895)

SRCR

SRCR: Scavenger receptor cysteine-rich domain (903 - 1000)

SRCR

SRCR: Scavenger receptor cysteine-rich domain (1039 - 1136)

SRCR

SRCR: Scavenger receptor cysteine-rich domain (1149 - 1243)

SRCR

SRCR: Scavenger receptor cysteine-rich domain (1250 - 1346)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1453 a.a.
蛋白主名 其他名称

scavenger receptor cysteine-rich type 1 protein M160

CD163 antigen B

关联疾病

疾病名称 别名
Diverticulitis
Contagious Pustular Dermatitis

Ecthyma, Contagious

Orf

Ecthyma Contagiosum

Scabby Mouth

Sheep Pox

Thistle Disease

Contagious Pustular Dermatosis

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma