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  2. Hsph1 - heat shock protein family H (Hsp110) member 1 Gene

Hsph1 - heat shock protein family H (Hsp110) member 1 Gene

中文名称:热休克蛋白家族 H (Hsp110) 成员 1

种属: Rattus norvegicus

同用名: Hsp105

基因 ID: 288444 | 基因类型: protein coding

关于 Hsph1

Primary_assembly 12: 5,390,922-5,410,224 forward strand.mRatBN7.2:CM026985.1

This gene has 4 transcripts (splice variants), 158 orthologues, 13 paralogues and is associated with 1 phenotype. Biased expression in Brain (RPKM 213.3), Kidney (RPKM 139.4) and 9 other tissues.

功能概要

预测该基因编码的蛋白可实现腺苷酸交换因子活性和α-微管蛋白结合活性。预计参与催化活性的调节。预计在几个过程的上游或内部起作用,包括伴侣辅因子依赖性蛋白质重折叠;细胞内信号转导的负调节;氮化合物代谢过程的正向调控。预测位于细胞质和核质中。预计是含蛋白质复合物的一部分。预计在胞质溶胶和细胞核中有活性。预测与微管共定位。与人类 HSPH1(热休克蛋白家族 H (Hsp110) 成员 1)同源。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable adenyl-nucleotide exchange factor activity and alpha-tubulin binding activity. Predicted to be involved in regulation of catalytic activity. Predicted to act upstream of or within several processes, including chaperone cofactor-dependent protein refolding; negative regulation of intracellular signal transduction; and positive regulation of nitrogen compound metabolic process. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be part of protein-containing complex. Predicted to be active in cytosol and nucleus. Predicted to colocalize with microtubule. Orthologous to human HSPH1 (heat shock protein family H (Hsp110) member 1). [provided by Alliance of Genome Resources, Apr 2022]

Hsph1 基因产物(1)

mRNA Protein Name
NM_001011901.2 NP_001011901.1 heat shock protein 105 kDa

Hsph1 蛋白结构

HSPH1_NBD

HSPH1_NBD: cd11739 (1 - 383)

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  • 858 a.a.
蛋白主名 其他名称

heat shock protein 105 kDa

heat shock 105/110 protein 1

heat shock 105kDa

heat shock 105kDa/110kDa protein 1

heat shock 110 kDa protein

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hsph1 NCBI NCBI:10808