Pak6 - p21 (RAC1) activated kinase 6 Gene

中文名称：p21 (RAC1) 激活激酶 6

种属: Rattus norvegicus

关于 Pak6

功能概要

预测该基因编码的蛋白可启动蛋白质丝氨酸/苏氨酸激酶活性。预计参与细胞内信号转导；蛋白质磷酸化；和 MAPK 级联的调节。预计在学习或记忆的上游或之内起作用；运动行为；和神经元投射形态发生。预测位于细胞连接处；纤维中心;和核质。预计在细胞质中有活性。该基因的人类直系同源物与透明细胞肾细胞癌有关。与多个人类基因同源，包括 BUB1B-PAK6（BUB1B-PAK6 通读）。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction; protein phosphorylation; and regulation of MAPK cascade. Predicted to act upstream of or within learning or memory; locomotory behavior; and neuron projection morphogenesis. Predicted to be located in cell junction; fibrillar center; and nucleoplasm. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in clear cell renal cell carcinoma. Orthologous to several human genes including BUB1B-PAK6 (BUB1B-PAK6 readthrough). [provided by Alliance of Genome Resources, Apr 2022]