2. Gene
  3. Parp14 - poly (ADP-ribose) polymerase family, member 14 Gene

Parp14 - poly (ADP-ribose) polymerase family, member 14 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：聚 (ADP-核糖) 聚合酶家族，成员 14

种属: Rattus norvegicus

同用名: RGD1310490

基因 ID: 303903 | 基因类型: protein coding

关于 Parp14

Primary_assembly 11: 64,902,785-64,934,916 forward strand.mRatBN7.2:CM026984.1

This gene has 2 transcripts (splice variants), 295 orthologues, 7 paralogues and is associated with 2 phenotypes. Biased expression in Spleen (RPKM 449.8), Adrenal (RPKM 332.7) and 9 other tissues.

功能概要

预计该基因编码的蛋白可启动多项功能，包括 NAD+ 绑定活动；戊糖基转移酶活性；和转录辅阻遏物活性。预计参与多个过程，包括蛋白质ADP-核糖基化；调节细胞因子介导的信号通路； STAT 蛋白酪氨酸磷酸化的调控。预测位于胞质溶胶和质膜中。预计在细胞质和细胞核中有活性。与人类 PARP14（聚（ADP-核糖）聚合酶家族成员 14）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable several functions, including NAD+ binding activity; pentosyltransferase activity; and transcription corepressor activity. Predicted to be involved in several processes, including protein ADP-ribosylation; regulation of cytokine-mediated signaling pathway; and regulation of tyrosine phosphorylation of STAT protein. Predicted to be located in cytosol and plasma membrane. Predicted to be active in cytoplasm and nucleus. Orthologous to human PARP14 (poly(ADP-ribose) polymerase family member 14). [provided by Alliance of Genome Resources, Apr 2022]

Parp14 基因产物(1)

mRNA Protein Name
NM_001191659.1 NP_001178588.1 protein mono-ADP-ribosyltransferase PARP14

Parp14 蛋白结构

RRM1_PAR14

RRM1_PAR14: cd12300 (5 - 87)

RRM_SF

RRM_SF: cl17169 (222 - 296)

Macro_Af1521_BAL-like

Macro_Af1521_BAL-like: cd02907 (791 - 949)

Macro_SF

Macro_SF: cl00019 (997 - 1176)

Macro_BAL-like

Macro_BAL-like: cd02903 (1206 - 1371)

TCCD_inducible_PARP_like

TCCD_inducible_PARP_like: cd01439 (1664 - 1784)

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  • 1787 a.a.
蛋白主名 其他名称

protein mono-ADP-ribosyltransferase PARP14

poly [ADP-ribose] polymerase 14

相关产品

Pre-clinical Phase
生物活性分子 (13)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-136979 RBN012759 Inhibitor 99.80% 否
HY-150207 RBN-3143 Inhibitor 99.24% 否
HY-148566 OUL232 Inhibitor 99.86% 否
HY-117889 PARP14 inhibitor H10 Inhibitor 98.04% 否
HY-108708 GeA-69 Inhibitor 99.91% 否
HY-148754 PARP10-IN-3 Inhibitor 98.89% 否
HY-143338 ART-IN-1 Inhibitor 98.91% 否
HY-121719 TIQ-A Inhibitor 99.65% 否
HY-155993 YCH1899 Inhibitor 99.39% 否
HY-148753 PARP10-IN-2 Inhibitor 98.02% 否
HY-W294889 OUL245 Inhibitor / 否
HY-148709 ARTD10/PARP10-IN-1 Inhibitor / 否
HY-148710 ARTD10/PARP10-IN-2 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Parp14 NCBI NCBI:54625
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