2. Gene
  3. ST8SIA6 - ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 Gene

ST8SIA6 - ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：ST8 α-N-乙酰神经氨酸 α-2,8-唾液酸转移酶 6

种属: Homo sapiens

同用名: SIA8F; SIAT8F; SIAT8-F; ST8SiaVI; ST8SIA-VI

基因 ID: 338596 | 基因类型: protein coding

关于 ST8SIA6

Cytogenetic location: 10p12.33 Genomic coordinates (GRCh38): 10:17,315,421-17,454,595 (from NCBI)

This gene has 3 transcripts (splice variants), 125 orthologues and 5 paralogues. Broad expression in lung (RPKM 3.3), heart (RPKM 1.0) and 14 other tissues.

功能概要

该基因编码糖基转移酶 29 蛋白家族的成员。该蛋白质家族的成员合成唾液酸糖结合物。唾液酸化可能导致癌细胞产生多药耐药性。可变剪接导致多个转录本变体。[RefSeq 提供，2016 年 9 月]

This gene encodes a member of the Glycosyltransferase 29 protein family. Members of this protein family synthesize sialylglycoconjugates. Sialylation may contribute to multidrug resistance in Cancer cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]

ST8SIA6 基因产物(2)

mRNA Protein Name
NM_001004470.3 NP_001004470.1 alpha-2,8-sialyltransferase 8F isoform 1 precursor
NM_001345961.2 NP_001332890.1 alpha-2,8-sialyltransferase 8F isoform 2

ST8SIA6 蛋白结构

Glyco_transf_29

Glyco_transf_29: Glycosyltransferase family 29 (sialyltransferase) (135 - 392)

  • 0
  • 100
  • 200
  • 300
  • 398 a.a.
蛋白主名 其他名称

alpha-2,8-sialyltransferase 8F

ST8 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase 6

关联疾病

疾病名称 别名
Lice Infestation

Pediculosis

Louse Infestation

Mixed Pediculosis

Lice Infestations

Infestation By Pediculus

Mixed Pediculosis Infestation

Pediculosis + Lice

Pediculosis And Phthirus Infection

Pediculosis And Phthirus Infections

Pediculosis And Phthirus Infestation

Infestation By Anoplura

Pediculus Infestation

Lice Nos
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-E70302 ST8 alpha-2,8-Sialyltransferase 6 / 否
HY-RS13860 ST8SIA6 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus ST8SIA6 MGD MGI:2386797
Rattus norvegicus ST8SIA6 RGD RGD:1303161
Bos taurus ST8SIA6 VGNC VGNC:35347
Canis familiaris ST8SIA6 VGNC VGNC:46868
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