1. Gene
  2. Esrrg - estrogen-related receptor gamma Gene

Esrrg - estrogen-related receptor gamma Gene

中文名称:雌激素相关受体 γ

种属: Rattus norvegicus

同用名: errg

基因 ID: 360896 | 基因类型: protein coding

关于 Esrrg

Primary_assembly 13: 99,564,669-99,783,397 forward strand.mRatBN7.2:CM026986.1

This gene has 2 transcripts (splice variants), 136 orthologues, 8 paralogues and is associated with 5 phenotypes. Biased expression in Kidney (RPKM 75.2), Heart (RPKM 5.1) and 6 other tissues.

功能概要

预计该基因编码的蛋白可启动多项功能,包括 AF-2 域绑定活动; DNA 结合转录因子活性,RNA 聚合酶 II 特异性;和相同的蛋白质结合活性。预计参与冷诱导产热的正调节和 RNA 聚合酶 II 转录的正调节。预测位于核内。与人类 ESRRG(雌激素相关受体γ)同源。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable several functions, including AF-2 domain binding activity; DNA-binding transcription factor activity, RNA polymerase II-specific; and identical protein binding activity. Predicted to be involved in positive regulation of cold-induced thermogenesis and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Orthologous to human ESRRG (estrogen related receptor gamma). [provided by Alliance of Genome Resources, Apr 2022]

Esrrg 基因产物(2)

mRNA Protein Name
NM_001401443.1 NP_001388372.1 estrogen-related receptor gamma isoform 1
NM_203336.3 NP_976081.1 estrogen-related receptor gamma isoform 2

Esrrg 蛋白结构

NR_DBD_ERR

NR_DBD_ERR: cd07170 (121 - 217)

NR_LBD_ERR

NR_LBD_ERR: cd06946 (236 - 455)

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  • 458 a.a.
蛋白主名 其他名称

estrogen-related receptor gamma

estrogen receptor-related protein 3

nuclear receptor subfamily 3 group B member 3

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Esrrg NCBI NCBI:2104