PNPLA2 - patatin-like phospholipase domain containing 2 Gene

中文名称：含 patatin 样磷脂酶结构域 2

种属: Rattus norvegicus

同用名: RGD1309044

关于 PNPLA2

功能概要

预计该基因编码的蛋白可启动视黄醇棕榈酸酯酶活性和甘油三酯脂肪酶活性。预计参与多个过程，包括酰基甘油代谢过程；甘油三酯螯合的负调节；和甘油三酯分解代谢过程的正调节。预计在细胞脂质分解代谢过程和脂滴组织的上游或内部起作用。预计位于胞质溶胶和核质中。预计在细胞质中有活性；脂滴;和膜。与人 PNPLA2 同源（含有 2 的 patatin 样磷脂酶结构域）。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable retinyl-palmitate esterase activity and triglyceride Lipase activity. Predicted to be involved in several processes, including acylglycerol metabolic process; negative regulation of sequestering of triglyceride; and positive regulation of triglyceride catabolic process. Predicted to act upstream of or within cellular lipid catabolic process and lipid droplet organization. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in cytoplasm; lipid droplet; and membrane. Orthologous to human PNPLA2 (patatin like Phospholipase domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]