Itk - IL2-inducible T-cell kinase Gene

中文名称：IL2 诱导型 T 细胞激酶

种属: Rattus norvegicus

关于 Itk

功能概要

预计该基因编码的蛋白可启动非跨膜蛋白酪氨酸激酶活性。预计参与多个过程，包括T细胞激活；激活磷脂酶 C 活性；和抗原受体介导的信号通路。预计位于多个细胞成分中，包括细胞-细胞连接；胞质溶胶；和核。该基因的人类直系同源物与淋巴增生综合征 1 相关。与人类 ITK（IL2 诱导型 T 细胞激酶）直系同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable non-membrane spanning protein tyrosine kinase activity. Predicted to be involved in several processes, including T cell activation; activation of Phospholipase C activity; and antigen receptor-mediated signaling pathway. Predicted to be located in several cellular components, including cell-cell junction; cytosol; and nucleus. Human ortholog(s) of this gene implicated in lymphoproliferative syndrome 1. Orthologous to human Itk (IL2 inducible T cell kinase). [provided by Alliance of Genome Resources, Apr 2022]