1. Gene
  2. INSL4 - insulin like 4 Gene

INSL4 - insulin like 4 Gene

中文名称:胰岛素样 4

种属: Homo sapiens

同用名: EPIL; PLACENTIN

基因 ID: 3641 | 基因类型: protein coding

关于 INSL4

Cytogenetic location: 9p24.1 Genomic coordinates (GRCh38): 9:5,231,419-5,235,304 (from NCBI)

This gene has 1 transcript (splice variant), 64 orthologues and 3 paralogues. Restricted expression toward placenta (RPKM 30.0).

功能概要

INSL4 编码胰岛素样蛋白 4,它是胰岛素超家族的一员。 INSL4 编码一个前体,该前体经历翻译后切割以产生 3 条多肽链 AC,形成由所有三个链或仅由 A 和 B 链组成的三级结构。 INSL4 产物的表达发生在早期胎盘细胞滋养层和合体滋养层中。[RefSeq 提供,2008 年 7 月]

INSL4 encodes the insulin-like 4 protein, a member of the Insulin superfamily. INSL4 encodes a precursor that undergoes post-translational cleavage to produce 3 polypeptide chains, A-C, that form tertiary structures composed of either all three chains, or just the A and B chains. Expression of INSL4 products occurs within the early placental cytotrophoblast and syncytiotrophoblast. [provided by RefSeq, Jul 2008]

INSL4 基因产物(1)

mRNA Protein Name
NM_002195.2 NP_002186.1 early placenta insulin-like peptide precursor
蛋白主名 其他名称

early placenta insulin-like peptide

early placenta insulin-like peptide (EPIL)

重组 INSL4 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70833 INSL4 Protein, Human (HEK293, His) Q14641 (A26-T139) ≥95%

关联疾病

疾病名称 别名
Placenta Accreta
Chromosome 9p Deletion Syndrome

Monosomy 9p

Monosomy 9p Syndrome

Alfi Syndrome

9p Syndrome

Chromosome 9p Deletion

9p Deletion

9p Monosomy

Deletion 9p

Partial Monosomy 9p

9p Deletion Syndrome

9p- Syndrome

Alfi'S Syndrome

Chromosome 9, Partial Trisomy 9p

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma