2. Gene
  3. MAST4 - microtubule associated serine/threonine kinase family member 4 Gene

MAST4 - microtubule associated serine/threonine kinase family member 4 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：微管相关丝氨酸/苏氨酸激酶家族成员 4

种属: Homo sapiens

基因 ID: 375449 | 基因类型: protein coding

关于 MAST4

Cytogenetic location: 5q12.3 Genomic coordinates (GRCh38): 5:66,596,393-67,169,593 (from NCBI)

This gene has 21 transcripts (splice variants), 252 orthologues and 13 paralogues. Ubiquitous expression in esophagus (RPKM 3.2), fat (RPKM 2.7) and 23 other tissues.

功能概要

该基因编码微管相关丝氨酸/苏氨酸蛋白激酶的成员。该家族中的蛋白质包含一个结构域，该结构域使激酶能够确定其自身的支架以控制其激酶活性的影响。可变剪接导致编码不同异构体的多个转录变体。[RefSeq 提供，2014 年 3 月]

This gene encodes a member of the microtubule-associated serine/threonine protein kinases. The proteins in this family contain a domain that gives the kinase the ability to determine its own scaffold to control the effects of their kinase activities. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014]

MAST4 基因产物(12)

mRNA Protein Name
NM_001164664.2 NP_001158136.1 microtubule-associated serine/threonine-protein kinase 4 isoform 3
NM_001290226.2 NP_001277155.1 microtubule-associated serine/threonine-protein kinase 4 isoform 4
NM_001290227.2 NP_001277156.1 microtubule-associated serine/threonine-protein kinase 4 isoform 5
NM_001290228.2 NP_001277157.1 microtubule-associated serine/threonine-protein kinase 4 isoform 6
NM_001297651.2 NP_001284580.1 microtubule-associated serine/threonine-protein kinase 4 isoform 7
NM_001393524.1 NP_001380453.1 microtubule-associated serine/threonine-protein kinase 4 isoform 8
NM_001393525.1 NP_001380454.1 microtubule-associated serine/threonine-protein kinase 4 isoform 9
NM_001393526.1 NP_001380455.1 microtubule-associated serine/threonine-protein kinase 4 isoform 10
NM_001393527.1 NP_001380456.1 microtubule-associated serine/threonine-protein kinase 4 isoform 5
NM_001393528.1 NP_001380457.1 microtubule-associated serine/threonine-protein kinase 4 isoform 12
NM_015183.3 NP_055998.1 microtubule-associated serine/threonine-protein kinase 4 isoform 1
NM_198828.3 NP_942123.1 microtubule-associated serine/threonine-protein kinase 4 isoform 2

MAST4 蛋白结构

DUF1908

DUF1908: Domain of unknown function (DUF1908) (258 - 532)

Pkinase

Pkinase: Protein kinase domain (571 - 843)

PDZ

PDZ: PDZ domain (Also known as DHR or GLGF) (1169 - 1224)

  • 0
  • 500
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  • 2000
  • 2623 a.a.
蛋白主名 其他名称

microtubule-associated serine/threonine-protein kinase 4

关联疾病

疾病名称 别名
Spinocerebellar Ataxia 27

Spinocerebellar Ataxia Type 27

SCA27

Cerebellar Ataxia Autosomal Dominant Fgf14-Related

Vestibulocerebellar Disorder With Predominant Ocular Signs

Cerebellar Ataxia, Autosomal Dominant, Fgf14-Related

Nystagmus 4, Congenital, Autosomal Dominant, Formerly

Nys4, Formerly

Ataxia, Spinocerebellar, Type 27
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08164 MAST4 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta MAST4 VGNC VGNC:74534
Bos taurus MAST4 VGNC VGNC:58387
Canis familiaris MAST4 VGNC VGNC:43035
Mus musculus MAST4 MGD MGI:1918885
Rattus norvegicus MAST4 RGD RGD:1310139
Felis catus MAST4 VGNC VGNC:102250
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