HES3 - hes family bHLH transcription factor 3 Gene

中文名称：hes 家族 bHLH 转录因子 3

种属: Homo sapiens

同用名: bHLHb43

关于 HES3

功能概要

预测启用 DNA 结合转录抑制活性，RNA 聚合酶 II 特异性；邮箱绑定活动；和 N-box 绑定活动。预计参与多个过程，包括 Notch 信号通路；神经元分化的负调节；和神经发生的调节。预计在几个过程的上游或内部起作用，包括神经系统发育；调节神经元分化的时间； RNA 聚合酶 II 对转录的调控。预测是染色质的一部分。预计活跃于核心。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific; E-box binding activity; and N-box binding activity. Predicted to be involved in several processes, including Notch signaling pathway; negative regulation of neuron differentiation; and regulation of neurogenesis. Predicted to act upstream of or within several processes, including nervous system development; regulation of timing of neuron differentiation; and regulation of transcription by RNA polymerase II. Predicted to be part of chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]